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Biomedical Engineering, IEEE Reviews in

Volume 3: 2010

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Displaying Results 1 - 24 of 24
  • Table of contents

    Publication Year: 2010 , Page(s): C4
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  • IEEE Transactions on Biomedical Engineering information for authors

    Publication Year: 2010 , Page(s): C3
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  • 2010 Index IEEE Reviews in Biomedical Engineering Vol. 3

    Publication Year: 2010 , Page(s): 225 - 227
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  • ICORR 2011

    Publication Year: 2010 , Page(s): 224
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  • 5th International IEEE EMBS Conference on Neural Engineering

    Publication Year: 2010 , Page(s): 223
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  • Computer Based Guidance in the Modern Operating Room: A Historical Perspective

    Publication Year: 2010 , Page(s): 209 - 222
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (4719 KB) |  | HTML iconHTML  

    The past few decades have seen the introduction of many different and innovative approaches aimed at enhancing surgical technique. As microprocessors have decreased in size and increased in processing power, more sophisticated systems have been developed. Some systems have attempted to provide enhanced instrument control while others have attempted to provide tools for surgical guidance. These systems include robotics, image enhancements, and frame-based and frameless guidance procedures. In almost every case the system's design goals were achieved and surgical outcomes were enhanced, yet a vast majority of today's surgical procedures are conducted without the aid of these advances. As new tools are developed and existing tools refined, special attention to the systems interface and integration into the operating room environment will be required before increased utilization of these technologies can be realized. View full abstract»

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  • Retinal Imaging and Image Analysis

    Publication Year: 2010 , Page(s): 169 - 208
    Cited by:  Papers (25)  |  Patents (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (8288 KB) |  | HTML iconHTML  

    Many important eye diseases as well as systemic diseases manifest themselves in the retina. While a number of other anatomical structures contribute to the process of vision, this review focuses on retinal imaging and image analysis. Following a brief overview of the most prevalent causes of blindness in the industrialized world that includes age-related macular degeneration, diabetic retinopathy, and glaucoma, the review is devoted to retinal imaging and image analysis methods and their clinical implications. Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed. Special attention is given to quantitative techniques for analysis of fundus photographs with a focus on clinically relevant assessment of retinal vasculature, identification of retinal lesions, assessment of optic nerve head (ONH) shape, building retinal atlases, and to automated methods for population screening for retinal diseases. A separate section is devoted to 3-D analysis of OCT images, describing methods for segmentation and analysis of retinal layers, retinal vasculature, and 2-D/3-D detection of symptomatic exudate-associated derangements, as well as to OCT-based analysis of ONH morphology and shape. Throughout the paper, aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships. View full abstract»

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  • Bayesian Quantitative Electrophysiology and Its Multiple Applications in Bioengineering

    Publication Year: 2010 , Page(s): 155 - 168
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (555 KB) |  | HTML iconHTML  

    Bayesian interpretation of observations began in the early 1700s, and scientific electrophysiology began in the late 1700s. For two centuries these two fields developed mostly separately. In part that was because quantitative Bayesian interpretation, in principle a powerful method of relating measurements to their underlying sources, often required too many steps to be feasible with hand calculation in real applications. As computer power became widespread in the later 1900s, Bayesian models and interpretation moved rapidly but unevenly from the domain of mathematical statistics into applications. Use of Bayesian models now is growing rapidly in electrophysiology. Bayesian models are well suited to the electrophysiological environment, allowing a direct and natural way to express what is known (and unknown) and to evaluate which one of many alternatives is most likely the source of the observations, and the closely related receiver operating characteristic (ROC) curve is a powerful tool in making decisions. Yet, in general, many people would ask what such models are for, in electrophysiology, and what particular advantages such models provide. So to examine this question in particular, this review identifies a number of electrophysiological papers in bioengineering arising from questions in several organ systems to see where Bayesian electrophysiological models or ROC curves were important to the results that were achieved. View full abstract»

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  • Clustering Algorithms in Biomedical Research: A Review

    Publication Year: 2010 , Page(s): 120 - 154
    Cited by:  Papers (14)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1602 KB) |  | HTML iconHTML  

    Applications of clustering algorithms in biomedical research are ubiquitous, with typical examples including gene expression data analysis, genomic sequence analysis, biomedical document mining, and MRI image analysis. However, due to the diversity of cluster analysis, the differing terminologies, goals, and assumptions underlying different clustering algorithms can be daunting. Thus, determining the right match between clustering algorithms and biomedical applications has become particularly important. This paper is presented to provide biomedical researchers with an overview of the status quo of clustering algorithms, to illustrate examples of biomedical applications based on cluster analysis, and to help biomedical researchers select the most suitable clustering algorithms for their own applications. View full abstract»

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  • Dry-Contact and Noncontact Biopotential Electrodes: Methodological Review

    Publication Year: 2010 , Page(s): 106 - 119
    Cited by:  Papers (68)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1477 KB) |  | HTML iconHTML  

    Recent demand and interest in wireless, mobile-based healthcare has driven significant interest towards developing alternative biopotential electrodes for patient physiological monitoring. The conventional wet adhesive Ag/AgCl electrodes used almost universally in clinical applications today provide an excellent signal but are cumbersome and irritating for mobile use. While electrodes that operate without gels, adhesives and even skin contact have been known for many decades, they have yet to achieve any acceptance for medical use. In addition, detailed knowledge and comparisons between different electrodes are not well known in the literature. In this paper, we explore the use of dry/noncontact electrodes for clinical use by first explaining the electrical models for dry, insulated and noncontact electrodes and show the performance limits, along with measured data. The theory and data show that the common practice of minimizing electrode resistance may not always be necessary and actually lead to increased noise depending on coupling capacitance. Theoretical analysis is followed by an extensive review of the latest dry electrode developments in the literature. The paper concludes with highlighting some of the novel systems that dry electrode technology has enabled for cardiac and neural monitoring followed by a discussion of the current challenges and a roadmap going forward. View full abstract»

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  • Analog Integrated Circuits Design for Processing Physiological Signals

    Publication Year: 2010 , Page(s): 93 - 105
    Cited by:  Papers (10)  |  Patents (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1065 KB) |  | HTML iconHTML  

    Analog integrated circuits (ICs) designed for processing physiological signals are important building blocks of wearable and implantable medical devices used for health monitoring or restoring lost body functions. Due to the nature of physiological signals and the corresponding application scenarios, the ICs designed for these applications should have low power consumption, low cutoff frequency, and low input-referred noise. In this paper, techniques for designing the analog front-end circuits with these three characteristics will be reviewed, including subthreshold circuits, bulk-driven MOSFETs, floating gate MOSFETs, and log-domain circuits to reduce power consumption; methods for designing fully integrated low cutoff frequency circuits; as well as chopper stabilization (CHS) and other techniques that can be used to achieve a high signal-to-noise performance. Novel applications using these techniques will also be discussed. View full abstract»

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  • Optical Imaging Modalities for Biomedical Applications

    Publication Year: 2010 , Page(s): 69 - 92
    Cited by:  Papers (4)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1678 KB) |  | HTML iconHTML  

    Optical photographic imaging is a well known imaging method that has been successfully translated into biomedical applications such as microscopy and endoscopy. Although several advanced medical imaging modalities are used today to acquire anatomical, physiological, metabolic, and functional information from the human body, optical imaging modalities including optical coherence tomography, confocal microscopy, multiphoton microscopy, multispectral endoscopy, and diffuse reflectance imaging have recently emerged with significant potential for non-invasive, portable, and cost-effective imaging for biomedical applications spanning tissue, cellular, and molecular levels. This paper reviews methods for modeling the propagation of light photons in a biological medium, as well as optical imaging from organ to cellular levels using visible and near-infrared wavelengths for biomedical and clinical applications. View full abstract»

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  • Control of Hand Prostheses Using Peripheral Information

    Publication Year: 2010 , Page(s): 48 - 68
    Cited by:  Papers (27)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1434 KB) |  | HTML iconHTML  

    Several efforts have been carried out to enhance dexterous hand prosthesis control by impaired individuals. Choosing which voluntary signal to use for control purposes is a critical element to achieve this goal. This review presents and discusses the recent results achieved by using electromyographic signals, recorded either with surface (sEMG) or intramuscular (iEMG) electrodes, and electroneurographic (ENG) signals. The potential benefits and shortcomings of the different approaches are described with a particular attention to the definition of all the steps required to achieve an effective hand prosthesis control in the different cases. Finally, a possible roadmap in the field is also presented. View full abstract»

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  • Virtual and Augmented Medical Imaging Environments: Enabling Technology for Minimally Invasive Cardiac Interventional Guidance

    Publication Year: 2010 , Page(s): 25 - 47
    Cited by:  Papers (2)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1360 KB) |  | HTML iconHTML  

    Virtual and augmented reality environments have been adopted in medicine as a means to enhance the clinician's view of the anatomy and facilitate the performance of minimally invasive procedures. Their value is truly appreciated during interventions where the surgeon cannot directly visualize the targets to be treated, such as during cardiac procedures performed on the beating heart. These environments must accurately represent the real surgical field and require seamless integration of pre- and intra-operative imaging, surgical tracking, and visualization technology in a common framework centered around the patient. This review begins with an overview of minimally invasive cardiac interventions, describes the architecture of a typical surgical guidance platform including imaging, tracking, registration and visualization, highlights both clinical and engineering accuracy limitations in cardiac image guidance, and discusses the translation of the work from the laboratory into the operating room together with typically encountered challenges. View full abstract»

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  • In the Spotlight: Tissue Engineering

    Publication Year: 2010 , Page(s): 23 - 24
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (233 KB) |  | HTML iconHTML  

    There are numerous studies that are being conducted in elucidating the biophysical effects of cells. The papers highlighted in this review present several different approaches to tease out the contribution of multiple factors in these highly complex systems. As the field moves forward, the ability to perturb the in vivo cellular microenvironment in order to promote tissue regeneration will directly benefit from our understanding of the physical (and chemical) factors that regulate cell behavior. View full abstract»

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  • In the Spotlight: Neuroengineering

    Publication Year: 2010 , Page(s): 19 - 22
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (283 KB) |  | HTML iconHTML  

    Neuroengineering and neuroscience frontiers are being discussed in this report. The forum for grand challenges in neuroengineering that took place in Washington, DC, on May 7-8, 2010. The major themes covered were: brain-machine interface, decoding brain activity, brain as computer-information processor, reverse engineering the brain and functional neuroimaging. View full abstract»

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  • In the Spotlight: Health Information Systems

    Publication Year: 2010 , Page(s): 15 - 18
    Cited by:  Papers (2)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (273 KB) |  | HTML iconHTML  

    The realization of an health information systems for disease prevention is reported. Lifestyle management aspects are also dealt with along with business model framework for disease prevention. View full abstract»

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  • In the Spotlight: Cardiovascular Engineering

    Publication Year: 2010 , Page(s): 12 - 14
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (282 KB) |  | HTML iconHTML  

    This paper discusses about the electromechanical effect of rabbit ventricals and abnormalities caused by asynchronous electrical activation in perfusion and pump function. These applications are of paramount importance to therapies that employ pacing of the heart, and particularly cardiac resynchronization therapy (CRT). View full abstract»

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  • In the Spotlight: Biomedical Signal Processing

    Publication Year: 2010 , Page(s): 10 - 11
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    BSP is a well established discipline and constitutes the corner stone for the training of Biomedical Engineers both at undergraduate and at graduate levels. No basic curriculum on Biomedical Engineering could even exist without one or more BSP courses. All the advanced methods of signal processing (from traditional linear digital filtering up to non linear higher-order approaches) have been applied to BSP. The EEG signal, which is basically pseudo-stochastic, is a good example: the information contained in the original tracings, which are generally used for physiological or clinical interpretation, is hardly directly interpretable unless a more or less complicate pre-processing is done. This reasoning is obviously applicable, in different contexts, to other biomedical signals. View full abstract»

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  • In the Spotlight: Biomedical Imaging

    Publication Year: 2010 , Page(s): 7 - 9
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    This paper discussed some highlights on biomedical image processing. Some topics discussed were; diffusion tensor imaging, MR spectroscopy, cardiac 4D ultrasound,electron crystallography of proteins, and learning based medical computer vision. View full abstract»

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  • In the Spotlight: BioInstrumentation

    Publication Year: 2010 , Page(s): 3 - 6
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (324 KB) |  | HTML iconHTML  

    This paper discussed physiological measurement instrumentation for ambulatory/wearable physiological monitoring, cardio-pulmonary monitoring, activity monitoring, and biochemical monitoring. Future aspects also were discussed View full abstract»

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  • Editorial

    Publication Year: 2010 , Page(s): 1 - 2
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  • IEEE Reviews on Biomedical Engineering publication information

    Publication Year: 2010 , Page(s): C2
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  • [Front cover]

    Publication Year: 2010 , Page(s): C1
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Aims & Scope

The IEEE Reviews in Biomedical Engineering reviews the state-of-the-art and trends in the emerging field of biomedical engineering.

Full Aims & Scope

Meet Our Editors

Editor-in-Chief
Jose C. Principe
Department of Biomedical Engineering
University of Florida