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IEEE Engineering in Medicine and Biology Magazine

Issue 4 • July-Aug. 2009

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Displaying Results 1 - 25 of 32
  • IEEE Engineering in Medicine and Biology Magazine - Front cover

    Publication Year: 2009, Page(s): c1
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  • Table of contents

    Publication Year: 2009, Page(s):1 - 2
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  • On learning and discussing [From the Editor]

    Publication Year: 2009, Page(s):3 - 4
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  • Engineering the future of biomedicine [President's Message]

    Publication Year: 2009, Page(s): 5
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  • Validation and verification [Letters to the Editor]

    Publication Year: 2009, Page(s):6 - 7
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  • Meetings and conferences [Society News]

    Publication Year: 2009, Page(s):8 - 9
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  • EMBC 2009 at a glance. . . [Student's Corner]

    Publication Year: 2009, Page(s):10 - 11
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  • The opposite of rube [Student Activities]

    Publication Year: 2009, Page(s):12 - 13
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  • IEEE Engineering in Medicine and Biology Magazine - Statement of Editorial Policy

    Publication Year: 2009, Page(s): 13
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  • EMBC 2009

    Publication Year: 2009, Page(s):14 - 15
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  • Computational techniques and pattern recognition [Introduction to the special issue]

    Publication Year: 2009, Page(s):16 - 18
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  • Comparative genomic workflow

    Publication Year: 2009, Page(s):19 - 24
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (724 KB) | HTML iconHTML

    This article describes a workflow for identifying conserved patterns in noncoding regions of vertebrate genomes, with an intention of investigating possible functions of the conserved regions. The annotations of genomes are collected from the Ensembl database. The sequences are then arranged to use for sequence alignment with basic local alignment search tool Z (BLASTZ) [10], which finds gap- free... View full abstract»

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  • Variable-length haplotype construction for geneߝgene interaction studies

    Publication Year: 2009, Page(s):25 - 31
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (787 KB) | HTML iconHTML

    Genetic epidemiology is a research field that aims to identify genetic polymorphisms that are involved in disease susceptibility. In this article, a variable-length haplotype construction for gene-gene interaction (VarHAP) technique is proposed. The technique will involve nonparametric classification where haplotypes inferred from multiple single nucleotide polymorphism (SNP) data are the classifi... View full abstract»

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  • Time-series approach to protein classification problem

    Publication Year: 2009, Page(s):32 - 37
    Cited by:  Papers (2)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (384 KB) | HTML iconHTML

    In this paper, a wavelet-based time-series approach for protein classification problem was presented. A novel feature vector based on the variation of seven physicochemical properties (hydrophobicity, electronic, isoelectric point, polarity, volume, composition, and molecular weight) of amino acids was proposed in this article. The feature vector contains the wavelet variance information of physic... View full abstract»

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  • Structural building blocks

    Publication Year: 2009, Page(s):38 - 44
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1078 KB) | HTML iconHTML

    The paper proposes a modified version of the mountain clustering method (MCM) to find a library of structural building blocks for the construction of three-dimensional (3-D) structures of proteins. The algorithm decides on building blocks based on a measure of local density of structural patterns. The algorithm was tested on a well-known data set and found it to successfully reconstruct a set of 7... View full abstract»

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  • Degree of differential prioritization

    Publication Year: 2009, Page(s):45 - 51
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1565 KB) | HTML iconHTML

    Because of the high dimensionality of the microarray data sets, feature selection (FS) has become an important challenge in molecular classification. Using the degree of differential prioritization (DDP) between relevance and antiredundancy, our proposed DDP-based FS technique is capable of achieving better accuracies than those previously reported, using a smaller predictor set. However, previous... View full abstract»

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  • Multicellular pattern formation

    Publication Year: 2009, Page(s):52 - 57
    Cited by:  Papers (2)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (781 KB) | HTML iconHTML

    Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. Although high-throughput data have become available with the advances in experimental technologies at a large scale, measuring gene expression levels at a high spatial resolution remains extremely difficult. As a result,... View full abstract»

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  • Data-driven approach to predict survival of cancer patients

    Publication Year: 2009, Page(s):58 - 66
    Cited by:  Papers (10)  |  Patents (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (2471 KB) | HTML iconHTML

    We develop a novel method to identify patients 'with different disease risk level. Our method estimates the optimal partition (cutoff) of a single gene's expression level by maximizing the separation of the survival curves related to the high- and low risk of the disease behavior. We extend our approach to construct two-gene signatures, which can exhibit synergetic influence on patient survival. U... View full abstract»

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  • Searching of optimal vaccination schedules

    Publication Year: 2009, Page(s):67 - 72
    Cited by:  Papers (2)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1832 KB) | HTML iconHTML

    Genetic algorithms (GAs) are a particular class of evolutionary algorithms that use techniques inspired by evolutionary biology. These are widely used in different areas of bioinformatics. In immunoinformatics, a common optimization problem is the search of optimal vaccination schedules. The problem of defining optimal schedules is particularly acute in cancer immunopreventive approaches, which re... View full abstract»

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  • Peptide binding to major histocompatibility complex

    Publication Year: 2009, Page(s):73 - 77
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (568 KB) | HTML iconHTML

    Peptide binding to major histocompatibility complex (MHC) molecules is a prerequisite for initiating an immune response. This article first describes an approach to predict MHC-peptide-binding sites by using an evolutionary algorithm (EA). The predicted binders are subsequently characterized for their physicochemical properties. The details and implementation issues of the peptide-binding predicti... View full abstract»

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  • From Frankenstein to the pacemaker

    Publication Year: 2009, Page(s):78 - 84
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (6696 KB) | HTML iconHTML

    This article provides an overview of the development, collections, exhibits, and programs of Bakken Museum, the world's only museum devoted to the history and science of electricity in life. View full abstract»

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  • Effect of microgravity on immune cell viability and proliferation

    Publication Year: 2009, Page(s):85 - 90
    Cited by:  Papers (6)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (706 KB) | HTML iconHTML

    Exposure to microgravity may produce changes in the performance of the immunological system at the cellular level and in the major physiological systems of the body. Weightlessness suppresses the lymphocytic functions involved in the immunity process, such as cell locomotion and expression of antigen. The present study was designed to investigate whether the proliferation and viability of lymphocy... View full abstract»

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  • Favorite places in the Twin Cities

    Publication Year: 2009, Page(s):91 - 93
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  • Medical Device Design for Six Sigma: A Road Map for Safety and Effectiveness (El-Haik, B.S. and Mekki, K.S.; 2008) [Book reviews]

    Publication Year: 2009, Page(s): 94
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  • Biomaterials--The Intersection of Biology and Materials Science (Temenoff, J.S. et al.; 2008) [Book reviews]

    Publication Year: 2009, Page(s):94 - 94, 100
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Aims & Scope

IEEE Engineering in Medicine and Biology Magazine contains articles on current technologies and methods used in biomedical and clinical engineering.

 

This Magazine ceased publication in 2010. The current retitled publication is IEEE Pulse.

Full Aims & Scope