Early Access ArticlesEarly Access articles are made available in advance of the final electronic or print versions. Early Access articles are peer reviewed but may not be fully edited. They are fully citable from the moment they appear in IEEE Xplore.
Nanosecond electric pulses are an effective power source in plasma medicine and biological stimulation, in which biophysical responses are governed by peak power and not energy. While uniphasic nanosecond pulse generators are widely available, the recent discovery that biological effects can be uniquely modulated by reversing the polarity of nanosecond duration pulses calls for the development of ... View full abstract»
Robotic ultrasound systems have turned into clinical use over the past few decades, increasing precision and quality of medical operations. In this paper, we propose a fully automatic scanning system for three-dimensional (3-D) ultrasound imaging. A depth camera was first used to obtain the depth data and color data of the tissue surface. Based on the depth image, the 3-D contour of the tissue was... View full abstract»
Ultracompact Implantable Design With Integrated Wireless Power Transfer and RF Transmission CapabilitiesPublication Year: 2018, Page(s):1 - 11
This paper presents an ultracompact design of biomedical implantable devices with integrated wireless power transfer (WPT) and RF transmission capabilities for implantable medical applications. By reusing the spiral coil in an implantable device, both RF transmission and WPT are realized without the performance degradation of both functions in ultracompact size. The complete theory of WPT based on... View full abstract»
Prior work has shown that compact analog circuits can faithfully represent and model fundamental biomolecular circuits via efficient log-domain cytomorphic transistor equivalents. Such circuits have emphasized basis functions that are dominant in genetic transcription and translation networks and deoxyribonucleic acid (DNA)-protein binding. Here, we report a system featuring digitally programmable... View full abstract»
Fast and Precise Emulation of Stochastic Biochemical Reaction Networks With Amplified Thermal Noise in Silicon ChipsPublication Year: 2018, Page(s):1 - 11
The analysis and simulation of complex interacting biochemical reaction pathways in cells is important in all of systems biology and medicine. Yet, the dynamics of even a modest number of noisy or stochastic coupled biochemical reactions is extremely time consuming to simulate. In large part, this is because of the expensive cost of random number and Poisson process generation and the presence of ... View full abstract»
A Scalable ISFET Sensing and Memory Array With Sensor Auto-Calibration for On-Chip Real-Time DNA DetectionPublication Year: 2018, Page(s):1 - 12
This paper presents a novel CMOS-based system-on-chip with a 78 $times$ 56 ion-sensitive field-effect transistor array using in-pixel quantization and compensation of sensor nonidealities. The pixel integrates sensing circuitry and memory cells to encode the ion concentration in time and store a calibration value per pixel. Temperature sensing pixels spread throughout... View full abstract»
A Real-Time Reconfigurable Multichip Architecture for Large-Scale Biophysically Accurate Neuron SimulationPublication Year: 2018, Page(s):1 - 12
Simulation of brain neurons in real-time using biophysically meaningful models is a prerequisite for comprehensive understanding of how neurons process information and communicate with each other, in effect efficiently complementing in-vivo experiments. State-of-the-art neuron simulators are, however, capable of simulating at most few tens/hundreds of biophysically accurate neurons in real-... View full abstract»
Aims & Scope
IEEE Transactions on Biomedical Circuits and Systems (TBioCAS) addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the IEEE Circuits and Systems Society to a wide variety of related areas.
General, theoretical, and application-oriented papers in the biomedical technical area with a Circuits and Systems perspective are encouraged for publication in TBioCAS. To be considered in scope, submissions to TBioCAS must demonstrate synergies between circuits and systems and medicine/biology.
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