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IEEE/ACM Transactions on Computational Biology and Bioinformatics

Issue 1 • Jan.-March 2004

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Displaying Results 1 - 13 of 13
  • [Front cover]

    Publication Year: 2004, Page(s): c1
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  • [Inside front cover]

    Publication Year: 2004, Page(s): c2
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  • Welcome Message

    Publication Year: 2004, Page(s): 1
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  • Introduction to the IEEE/ACM Transactions on Computational Biology and Bioinformatics

    Publication Year: 2004, Page(s):2 - 3
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  • Introduction of new Associate Editors

    Publication Year: 2004, Page(s):4 - 12
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  • Phylogenetic networks: modeling, reconstructibility, and accuracy

    Publication Year: 2004, Page(s):13 - 23
    Cited by:  Papers (72)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1113 KB) | HTML iconHTML

    Phylogenetic networks model the evolutionary history of sets of organisms when events such as hybrid speciation and horizontal gene transfer occur. In spite of their widely acknowledged importance in evolutionary biology, phylogenetic networks have so far been studied mostly for specific data sets. We present a general definition of phylogenetic networks in terms of directed acyclic graphs (DAGs) ... View full abstract»

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  • Biclustering algorithms for biological data analysis: a survey

    Publication Year: 2004, Page(s):24 - 45
    Cited by:  Papers (698)  |  Patents (19)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1251 KB) | HTML iconHTML

    A large number of clustering approaches have been proposed for the analysis of gene expression data obtained from microarray experiments. However, the results from the application of standard clustering methods to genes are limited. This limitation is imposed by the existence of a number of experimental conditions where the activity of genes is uncorrelated. A similar limitation exists when cluste... View full abstract»

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  • Sequencing-by-hybridization revisited: the analog-spectrum proposal

    Publication Year: 2004, Page(s):46 - 52
    Cited by:  Papers (315)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (320 KB) | HTML iconHTML

    All published approaches to DNA sequencing by hybridization (SBH) consist of the biochemical acquisition of the spectrum of a target sequence (the set of its subsequences conforming to a given probing pattern) followed by the algorithmic reconstruction of the sequence from its spectrum. In the "standard" or "uniform" approach, the probing pattern is a string of length L and the length of reliably ... View full abstract»

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  • Pure multiple RNA secondary structure alignments: a progressive profile approach

    Publication Year: 2004, Page(s):53 - 62
    Cited by:  Papers (56)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (2190 KB) | HTML iconHTML

    In functional, noncoding RNA, structure is often essential to function. While the full 3D structure is very difficult to determine, the 2D structure of an RNA molecule gives good clues to its 3D structure, and for molecules of moderate length, it can be predicted with good reliability. Structure comparison is, in analogy to sequence comparison, the essential technique to infer related function. We... View full abstract»

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  • [Advertisement]

    Publication Year: 2004, Page(s): 63
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  • Call for Papers

    Publication Year: 2004, Page(s): 64
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  • IEEE/ACM TCBB: Information for authors

    Publication Year: 2004, Page(s): c3
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  • [Back cover]

    Publication Year: 2004, Page(s): c4
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Aims & Scope

This bimonthly publishes archival research results related to the algorithmic, mathematical, statistical, and computational methods that are central in bioinformatics and computational biology.

Full Aims & Scope

Meet Our Editors

Editor-in-Chief
Aidong Zhang, PhD, IEEE Fellow
Dept. of Computer Science and Engineering
State University of New York at Buffalo
Buffalo, New York 14260 USA
azhang@buffalo.edu

Associate Editor-in-Chief
Dong Xu
University of Missouri
xudong@missouri.edu