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Proceedings of the IEEE

Issue 1 • Date Jan. 2004

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Displaying Results 1 - 22 of 22
  • Proceedings of the IEEE January 2004

    Publication Year: 2004, Page(s): 0_1
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  • Proceedings of the IEEE celebrating 92 years of in-depth coverage on emerging technologies

    Publication Year: 2004, Page(s): 0_2
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  • Table of contents

    Publication Year: 2004, Page(s): 1
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  • Proceedings of the IEEE Society Information

    Publication Year: 2004, Page(s): 2
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  • Special Issue on Biomedical Applications for MEMS and Microfluidics

    Publication Year: 2004, Page(s):3 - 5
    Cited by:  Papers (5)
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  • A BioMEMS review: MEMS technology for physiologically integrated devices

    Publication Year: 2004, Page(s):6 - 21
    Cited by:  Papers (135)  |  Patents (57)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (288 KB) | HTML iconHTML

    MEMS devices are manufactured using similar microfabrication techniques as those used to create integrated circuits. They often, however, have moving components that allow physical or analytical functions to be performed by the device. Although MEMS can be aseptically fabricated and hermetically sealed, biocompatibility of the component materials is a key issue for MEMS used in vivo. Interest in M... View full abstract»

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  • Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments

    Publication Year: 2004, Page(s):22 - 42
    Cited by:  Papers (122)  |  Patents (10)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (960 KB) | HTML iconHTML

    As the molecular origins of disease are better understood, the need for affordable, rapid, and automated technologies that enable microscale molecular diagnostics has become apparent. Widespread use of microsystems that perform sample preparation and molecular analysis could ensure that the benefits of new biomedical discoveries are realized by a maximum number of people, even those in environment... View full abstract»

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  • Applications of MEMS in surgery

    Publication Year: 2004, Page(s):43 - 55
    Cited by:  Papers (68)  |  Patents (11)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (720 KB) | HTML iconHTML

    In the past few decades, microelectromechanical systems (MEMS) have found themselves being adopted into a wide variety of fields and disciplines. Recently there has been an increased interest in the use of MEMS for surgical applications. MEMS technology has the potential to not only improve the functionality of existing surgical devices, but also add new capabilities, which allow surgeons to devel... View full abstract»

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  • Microsystems for drug and gene delivery

    Publication Year: 2004, Page(s):56 - 75
    Cited by:  Papers (42)  |  Patents (10)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1832 KB) | HTML iconHTML

    Microneedles and other structures have been developed for introducing therapeutic agents into tissues and cells. Microstructures for transdermal delivery hold the promise of pain-free drug injection. Electrodes integrated with microneedles can sense and monitor the effects of injected materials on tissues. Microprobes have been shown to be effective in transfecting cells through the delivery of DN... View full abstract»

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  • Wireless implantable microsystems: high-density electronic interfaces to the nervous system

    Publication Year: 2004, Page(s):76 - 97
    Cited by:  Papers (250)  |  Patents (19)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1568 KB) | HTML iconHTML

    This paper describes the development of a high-density electronic interface to the central nervous system. Silicon micromachined electrode arrays now permit the long-term monitoring of neural activity in vivo as well as the insertion of electronic signals into neural networks at the cellular level. Efforts to understand and engineer the biology of the implant/tissue interface are also underway. Th... View full abstract»

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  • Biomedical microsystems for minimally invasive diagnosis and treatment

    Publication Year: 2004, Page(s):98 - 114
    Cited by:  Papers (43)  |  Patents (6)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1176 KB) | HTML iconHTML

    Great significant progress has been made in the development of biomedical microdevices in recent years, and these devices are now playing an important role in diagnosis and therapy. This paper presents a review of applications of microelectromechanical systems (MEMS) devices for in vivo diagnosis and therapy, and endoscopic- and catheter-based interventions. MEMS technology has enabled the further... View full abstract»

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  • β-galactosidase assays of single-cell lysates on a microchip: a complementary method for enzymatic analysis of single cells

    Publication Year: 2004, Page(s):115 - 125
    Cited by:  Papers (17)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (448 KB) | HTML iconHTML

    The use of microfluidic glass chips for continuous single-cell lysis and assay of internal β-Galactosidase (β-Gal) content is described. Cells were transported single file toward a Y-shaped mixing junction at which lytic agents were introduced by suction. Flow velocities of ∼100 and ∼40 μm/s were used under protein denaturing [35 mM sodium dodecylsulfate (SDS)] and nondenaturi... View full abstract»

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  • Diffusion-based analysis of molecular interactions in microfluidic devices

    Publication Year: 2004, Page(s):126 - 139
    Cited by:  Papers (25)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (656 KB) | HTML iconHTML

    The study of molecular interactions in biological fluids is important as a research tool to elucidate molecular and biological function, for discovering or designing molecules that have a desirable function, and for measuring or detecting analytes for clinical diagnostic purposes. Microfluidics is an emerging technology that has proven useful for studying and controlling molecular interactions wit... View full abstract»

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  • Centrifuge-based fluidic platforms

    Publication Year: 2004, Page(s):140 - 153
    Cited by:  Papers (37)  |  Patents (7)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (632 KB) | HTML iconHTML

    In this paper, centrifuge-based microfluidic platforms are reviewed and compared with other popular microfluidic propulsion methods. The underlying physical principles of centrifugal pumping in microfluidic systems are presented and the various centrifuge fluidic functions such as valving, decanting, calibration, mixing, metering, heating, sample splitting, and separation are introduced. Those flu... View full abstract»

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  • Disposable smart lab on a chip for point-of-care clinical diagnostics

    Publication Year: 2004, Page(s):154 - 173
    Cited by:  Papers (176)  |  Patents (40)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1040 KB) | HTML iconHTML

    This paper presents the development of a disposable plastic biochip incorporating smart passive microfluidics with embedded on-chip power sources and integrated biosensor array for applications in clinical diagnostics and point-of-care testing. The fully integrated disposable biochip is capable of precise volume control with smart microfluidic manipulation without costly on-chip microfluidic compo... View full abstract»

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  • Reliability considerations for the BioMEMS designer

    Publication Year: 2004, Page(s):174 - 184
    Cited by:  Papers (3)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (184 KB) | HTML iconHTML

    The emerging field of biomedical microelectromechanical systems (bioMEMS) has the potential to revolutionize how drugs are discovered, how diseases are diagnosed, and how treatments are administered. Nevertheless, that potential is unlikely to translate into commercial success unless bioMEMS designers can prove that such novel functionality can be delivered each and every time without failure. The... View full abstract»

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  • Hall of fame for electrical engineers-Elihu Thomson

    Publication Year: 2004, Page(s):185 - 187
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (240 KB) | HTML iconHTML

    The Edison Medal was proposed in 1904 during the observance of the 25th anniversary of Thomas A. Edison's introduction of a successful electric lighting system. The medal was first given in 1909 with Elihu Thomson as the first recipient. He was cited for his "meritorious achievement in electrical science, engineering, and arts as exemplified in his contributions thereto during the past thirty year... View full abstract»

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  • Correction to “Networked Intelligent Robots Through the Internet: Issues and Opportunities”

    Publication Year: 2004, Page(s): 188
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  • Proceedings of the IEEE Future Special Issues

    Publication Year: 2004, Page(s):189 - 190
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  • IEEE copyright form

    Publication Year: 2004, Page(s):191 - 192
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  • IEEE Member Digital Library [advertisement]

    Publication Year: 2004, Page(s): 03
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  • Proceedings of the IEEE Check out our February Issue

    Publication Year: 2004, Page(s): 0_4
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Aims & Scope

The most highly-cited general interest journal in electrical engineering and computer science, the Proceedings is the best way to stay informed on an exemplary range of topics.

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Meet Our Editors

Editor-in-Chief
H. Joel Trussell
North Carolina State University