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Intelligent Systems, IEEE

Issue 6 • Date Nov-Dec 2001

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Displaying Results 1 - 17 of 17
  • Geno2pheno: interpreting genotypic HIV drug resistance tests

    Publication Year: 2001 , Page(s): 35 - 41
    Cited by:  Papers (12)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (281 KB)  

    This intelligent system uses information encoded in the HIV genomic sequence to predict the virus's resistance or susceptibility to drugs. To make predictions, geno2pheno employs decision tree classifiers and support vector machines. View full abstract»

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  • Human language technologies for knowledge management

    Publication Year: 2001 , Page(s): 84 - 94
    Cited by:  Papers (4)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (417 KB)  

    Knowledge management has changed the way we look at knowledge in the current economy; it is a key factor in an enterprise's success or failure. In contrast to what we as engineers typically love, KM puts people first organizational issues second, and technology third. Seriously considering these issues to produce a successful KM system leads to at least three requirements. We must: encourage emplo... View full abstract»

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  • The impact of European bioinformatics

    Publication Year: 2001 , Page(s): 18 - 19
    Cited by:  Papers (1)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (41 KB)  

    Europe is undergoing a political integration process, the goals of which are still under discussion. Some countries, such as Germany, France, Italy, Spain, Holland, and Belgium, have coordinated aspects of their economy, including a common currency, under the administration of the European Commission. Key countries such as the UK and Denmark are still undecided about their degree of participation,... View full abstract»

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  • Improving objectivity and scalability in protein crystallization

    Publication Year: 2001 , Page(s): 26 - 34
    Request Permissions | Click to expandAbstract | PDF file iconPDF (537 KB)  

    This article describes the application of image analysis techniques to protein crystallization experiment classification. By applying knowledge discovery techniques to the analysis results, we can extract important crystallographic knowledge. View full abstract»

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  • Sensor-based pedestrian protection

    Publication Year: 2001 , Page(s): 77 - 81
    Cited by:  Papers (47)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (609 KB)  

    Pedestrian accidents represent the second-largest source of traffic-related injuries and fatalities, after accidents involving car passengers. Children are especially at risk. A complementary approach to accident prevention is to focus on sensor-based solutions, which let vehicles "look ahead" and detect pedestrians in their surroundings. The article investigates the state of the art in this domai... View full abstract»

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  • Donald Michie: secrets of Colossus revealed

    Publication Year: 2001 , Page(s): 82 - 83
    Request Permissions | Click to expandAbstract | PDF file iconPDF (98 KB)  

    In 1943, Donald Michie, Alan Turing, and Jack Good were poised at the crossroads of AI. World War II, Hitler, German U-boats, and wartime code-breaking set the scene. Together they would take walks in the English countryside talking about various approaches, conjectures, and arguments concerning what today we call AI. They formed an intellectual cabal with a shared obsession with thinking machines... View full abstract»

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  • Crazy clocks: counterintuitive consequences of "intelligent" automation

    Publication Year: 2001 , Page(s): 74 - 76
    Cited by:  Papers (3)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (300 KB)  

    Human error is a widely recognized problem, and there are at least two complementary paths to error mitigation. One approach aims to reduce error by changing the design of systems and products to make them fit human capabilities and limitations. Another approach aims to remove human error (and human involvement) altogether by automation, sometimes including intelligent systems. The latter approach... View full abstract»

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  • The Asia-Pacific regional perspective on bioinformatics

    Publication Year: 2001 , Page(s): 19 - 61
    Request Permissions | Click to expandAbstract | PDF file iconPDF (342 KB)  

    The Asia-Pacific region spans the Asian and Australasian continents as well as the Pacific-rim countries. As such, the seeds of bioinformatics in this region have been sown as early as 1989 in India, followed by Japan and Australia in 1991. While bioinformatics research, service, and education have reached laudable heights in these countries as well as in Singapore, Taiwan, Korea, Malaysia, New Ze... View full abstract»

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  • Neuron function: the mystery persists

    Publication Year: 2001 , Page(s): 4 - 7
    Cited by:  Papers (1)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (293 KB)  

    There are currently three primary models of how neurons function, each with its uses and variations, according to James McClelland, a professor of psychology and computer science at Carnegie Mellon University and codirector of the Center for Neural Basis of Cognition. The first and simplest is the integrate-and-fire model, which is based on the idea that the neuron adds and subtracts excitatory an... View full abstract»

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  • Using combinatory categorial grammar to extract biomedical information

    Publication Year: 2001 , Page(s): 62 - 67
    Cited by:  Papers (2)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (119 KB)  

    Extracting information from biology databases manually can be an overwhelming task. GenBank, the US National Institutes of Health database containing all publicly available DNA sequences, has more than 14 billion bases in 13 million genetic-sequence records. Medline, a literature database available through PubMed, has over 11 million journal citations. In a May 2001 search request for "cytokine" (... View full abstract»

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  • Challenges for intelligent systems in biology

    Publication Year: 2001 , Page(s): 14 - 18
    Cited by:  Papers (6)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (66 KB) |  | HTML iconHTML  

    Biological processes have produced the ultimate intelligent system (humans), and now we are trying to understand biology (and ourselves) by building intelligent systems. Intelligent systems research in biology strives to understand how living systems perform difficult tasks routinely (ranging from molecular phenomena such as protein-folding to organism-level phenomena such as cognition). The defin... View full abstract»

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  • Automatic pattern embedding in protein structure models

    Publication Year: 2001 , Page(s): 21 - 25
    Cited by:  Papers (1)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (204 KB)  

    This article describes an implementation of a set of rules for automatically embedding a minimal functional sequence pattern in a structural hidden Markov model. The final product is a library of wide ranging fold models with encoded information about the functional families. View full abstract»

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  • Diagnosis systems in medicine with reusable knowledge components

    Publication Year: 2001 , Page(s): 68 - 73
    Cited by:  Papers (2)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (140 KB)  

    Constructing knowledge systems is viewed as a modeling activity for developing structured knowledge and reasoning models. To ensure well-formed models, the use of some knowledge engineering methodology is crucial. Additionally, reusing models can significantly reduce the time and costs of building a new application. Reusing knowledge components across different applications and domains can help ac... View full abstract»

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  • Toward more intelligent annotation tools: a prototype

    Publication Year: 2001 , Page(s): 42 - 51
    Cited by:  Papers (3)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (185 KB)  

    Several research teams have addressed the problem of annotating sequence data computationally, but no genetic tools have emerged to help gather information on a given sequence or set of sequences. The authors present Precis, a prototype tool that automatically creates protein reports from concise information. View full abstract»

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  • A knowledge base for integrated biological systems

    Publication Year: 2001 , Page(s): 52 - 61
    Request Permissions | Click to expandAbstract | PDF file iconPDF (199 KB)  

    Describes the creation of a knowledge base using AROM, a knowledge representation system that permits fine grained description of biological components and how they interact to create an integrated system. View full abstract»

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  • Intelligent systems in biology: why the excitement?

    Publication Year: 2001 , Page(s): 8 - 13
    Cited by:  Papers (3)
    Request Permissions | Click to expandAbstract | PDF file iconPDF (298 KB)  

    Biology has rapidly become a data-rich, information-hungry science because of recent massive data generation technologies. Our biological colleagues are designing more clever and informative experiments because of recent advances in molecular science. These experiments and data hold the key to the deepest secrets of biology and medicine, but we cannot fully analyze this data due to the wealth and ... View full abstract»

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  • Clips from the computists' weekly

    Publication Year: 2001 , Page(s): 95 - 98
    Request Permissions | Click to expandAbstract | PDF file iconPDF (71 KB) |  | HTML iconHTML  

    First Page of the Article
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Aims & Scope

IEEE Intelligent Systems serves users, managers, developers, researchers, and purchasers who are interested in intelligent systems and artificial intelligence, with particular emphasis on applications.

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Meet Our Editors

Editor-in-Chief
Daniel Zeng
University of Arizona