Notification:
We are currently experiencing intermittent issues impacting performance. We apologize for the inconvenience.
By Topic

Engineering in Medicine and Biology Magazine, IEEE

Issue 6 • Date Nov.-Dec. 1999

Filter Results

Displaying Results 1 - 12 of 12
  • "Engineering" the wound-healing process

    Publication Year: 1999 , Page(s): 22 - 26
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (405 KB)  

    Our group is studying the modulation of fibroblast behavior by various wound-healing agents. 3-D collagen gels were used as an in vitro wound model to study human dermal fibroblast behavior. In this article, we hypothesize that efficient contraction of the in vitro wound model is associated with gap junction (GJ) formation between cells and, conversely, that inhibition of the in vitro wound-model contraction is associated with inhibition of GJ between cells. We used chitosan-collagen blends as the in vitro wound model, investigating the contractile behavior of fibroblasts and the effect of chitosan on wound contraction and GJ formation. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Improving geometric model construction for blood flow modeling

    Publication Year: 1999 , Page(s): 33 - 39
    Cited by:  Papers (13)  |  Patents (22)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (711 KB)  

    We have applied an active contour method based on level sets to the problem of image-based model construction for computational hemodynamics. The geometric nature of the segmentation algorithm makes it suitable for use with solid modeling techniques. Using the methodology shown, we have constructed models that are appropriate for use with blood flow simulation applications. We are currently extending these methods to address limitations of the current approach, including issues related to 3-D geometric accuracy and mesh quality. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Fast and precise positioning of single cells on planar electrode substrates

    Publication Year: 1999 , Page(s): 48 - 52
    Cited by:  Papers (3)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (452 KB)  

    For cell biosensors and for studying neural networks using planar electrode substrates, a suitable technique for positioning single cells on electrodes was needed. We reported a new method for fast and efficient positioning of single cells on ring electrodes by controlled suction through holes. We described the microfabrication of electrode substrates with microholes and the cell positioning procedure. L929 cells and Neuro 2A cells could be positioned in parallel without cell damage. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Ideas to help break down barriers: the RESNA Student Scientific Paper/Paralyzed Veterans of America Student Design Competition winners

    Publication Year: 1999 , Page(s): 59 - 63
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (482 KB)  

    Each year, RESNA hosts two competitions at its annual conference. The RESNA Student Scientific Paper Competition promotes high-quality research related to the fields of rehabilitation engineering and assistive technology. The Paralyzed Veterans of America Student Design Competition recognizes exemplary projects developed by students from all disciplines related to assistive technology. Both competitions are intended to encourage students from a variety of disciplines to address issues in the field of assistive technology and submit papers for presentation at the annual RESNA conference. This article presents summaries of the 1999 competition winning entries which covered the following topics: relating wheelchair setup to propulsion biomechanics; gender differences in the kinematic features of manual wheelchair propulsion; comparison of side-to-side wheelchair propulsion forces using an ARMA modeling technique; feasibility of EEG control for a hand grasp neuroprosthesis; clinical use of in situ pressure sensors for prosthetic socket fit; bowling ramp modification to increase autonomy and normalization; passive robot for frail visually impaired people; a telephone device to improve communication; voice operated wheelchair; wheelchair-based mounting system for automated positioning of electronic augmentative communication device. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Synthesis and transformation of three-dimensional facial images

    Publication Year: 1999 , Page(s): 64 - 69
    Cited by:  Papers (1)  |  Patents (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (537 KB)  

    In this article, we enhance and extend 2-D methods by using texture-mapped laser-video depth data. Methods for the synthesis of new three-dimensional (3-D) facial images from a database of texture-mapped laser-scanned surfaces are described. Four methods are used to create new facial images. The first constructs average facial images from a sample of faces. The second exaggerates the difference between a subject and an average to create a caricature. The third method captures the difference between two averages, which can then be applied to individuals for statistical transformation. Finally, principal component analysis is used to find the major axes of facial variation in a sample, allowing the construction of completely novel faces from a small vector of values. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • A wireless near-infrared energy system for medical implants

    Publication Year: 1999 , Page(s): 70 - 72
    Cited by:  Papers (5)  |  Patents (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (257 KB)  

    A less invasive method for supplying light power to implant devices, we propose a new wireless energy source that employs a near-infrared laser with a photovoltaic cell. The system can also be used with a rechargeable battery. We discuss the configuration of the system, show its energy transfer efficiency, and discuss its performance during some basic experiments. View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Author Index

    Publication Year: 1999 , Page(s): 101 - 104
    Save to Project icon | Request Permissions | PDF file iconPDF (351 KB)  
    Freely Available from IEEE
  • Subject Index

    Publication Year: 1999 , Page(s): 104 - 112
    Save to Project icon | Request Permissions | PDF file iconPDF (658 KB)  
    Freely Available from IEEE
  • Estimating complexity from EEG background activity of epileptic patients

    Publication Year: 1999 , Page(s): 73 - 79
    Cited by:  Papers (2)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (468 KB)  

    We analyze the EEG background activities of five epileptic patients and compare them with the EEGs of five control subjects by means of methods from nonlinear dynamical system theory. We divided the EEG time-series data into frames to select those that fulfilled the stationarity condition, which is necessary in order to apply our methods. Then, we reconstructed the chaotic dynamic attractors expressed in the phase space and calculated their correlation dimensions, which are a measure of the complexity. Furthermore, we recorded an EEG during a petit mal epileptic seizure, whose attractor is a 3-D plot and the correlation dimension will also be presented View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Automated registration of brain images using edge and surface features

    Publication Year: 1999 , Page(s): 40 - 47
    Cited by:  Papers (2)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (480 KB)  

    We present an automated multimodality (CT & MRI) registration algorithm based on hierarchical feature extraction. Two kinds of shape representations-edge and surface-are extracted hierarchically from different image modalities. The registration then is performed using least-squares matching of the user-specified (but automatically extracted) corresponding features. In our implementation, the 3-D version of the Canny edge detector is employed in the extraction of corresponding edge information. An automatic segmentation algorithm is introduced to extract the corresponding surfaces from the edges efficiently. The geometric matching of those extracted shape features then is performed using the iterative closest-point matching method View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Micromachined needle arrays for drug delivery or fluid extraction

    Publication Year: 1999 , Page(s): 53 - 58
    Cited by:  Papers (12)  |  Patents (6)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (468 KB)  

    Micromachined needle arrays have been designed, fabricated, and characterized. The design includes arrays of 25 needles with fluid coupling channels and dual structural supports. Numerical modeling of fluid flow characteristics was performed, demonstrating that the needle coupling channels redistribute flow when the input or output ports are fully restricted. Micromachining technologies have been used to batch fabricate hollow metallic fluid coupled needle arrays. The significance of this work includes the development of the hollow metallic micromachined needle arrays for biomedical applications, as well as a discussion of structural, fluidic, and biological design considerations. The micromachined needle array has many advantages, including (a) reduced trauma at penetration site (small size), (b) greater freedom of patient movement (minimal penetration), (c) a practically pain-free drug delivery device (distribution of force), (d) precise control of penetration depth (needle extension length), and (e) they can be stacked and packaged into a 3-D device for fluid transfer View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.
  • Frequency response of evoked potential in normal and diseased nerve muscle

    Publication Year: 1999 , Page(s): 27 - 32
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (284 KB)  

    We examined the nerve-muscle response using principles of control theory. In vivo experiments allow control of other factors that may also influence muscle response. We propose that nerve-muscle response might consist of three transfer functions: nerve, end-plate, and muscle. In general, nerves can respond until about 1000 Hz stimulation, so the results of this experiment were not greatly influenced by the transfer functions of nerves. That is, the results of this study were influenced by the transfer function of end-plate and muscle. Ensuing research should, therefore, strive to identify individual peripheral nerve, end-plate, and muscle responses. Furthermore, in order to apply the results of this study to human muscle, the following matters need to be considered: (1) Our model does not take into account that the major part of human muscles are composed of different fiber types. (2) Muscle properties depend on age, metabolic and nutritional state, and on the level of muscular activity before the experiment. Our experiments demonstrated the controlling factors of nerve-muscle condition and have shown that the neuromuscular control system can be described by methods of control theory View full abstract»

    Full text access may be available. Click article title to sign in or learn about subscription options.

Aims & Scope

IEEE Engineering in Medicine and Biology Magazine contains articles on current technologies and methods used in biomedical and clinical engineering.

 

This Magazine ceased publication in 2010. The current retitled publication is IEEE Pulse.

Full Aims & Scope