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Health Informatics and Bioinformatics (HIBIT), 2010 5th International Symposium on

Date 20-22 April 2010

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Displaying Results 1 - 25 of 42
  • [Title page]

    Publication Year: 2010, Page(s): 1
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  • [Copyright notice]

    Publication Year: 2010, Page(s): 1
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  • Preface

    Publication Year: 2010, Page(s): 1
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  • Organization

    Publication Year: 2010, Page(s):1 - 2
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  • Table of contents

    Publication Year: 2010, Page(s):1 - 4
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  • ECG beat classification using discrete wavelet coefficients

    Publication Year: 2010, Page(s):1 - 6
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (284 KB) | HTML iconHTML

    In this work we have developed a new approach to identify different types of electrocardiogram (ECG) beats using discrete wavelet transform (DWT) coefficients. The purpose of the study is to develop a simple algorithm for the diagnosis of some cardiac abnormalities. Five types of cardiac phenomena are considered and for each of these some particular records from the MIT-BIH Arrhythmia Database are... View full abstract»

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  • Functional near infrared spectroscopy based congitive task classification using support vector machines

    Publication Year: 2010, Page(s):7 - 12
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (259 KB) | HTML iconHTML

    The present study analyzes brain hemodynamic concentration of frontal cortex during four cognitive mental tasks. The analysis procedure consists of three sequential steps. First, the strong brain activation regions have been investigated thoroughly from all subjects in order to find a proper electrode location that generates important brain stimuli. Second, a feature extraction method that is base... View full abstract»

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  • Combination of conventional regularization methods and genetic algorithm for solving the inverse problem of electrocardiography

    Publication Year: 2010, Page(s):13 - 20
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (808 KB) | HTML iconHTML

    Distribution of electrical potentials over the surface of the heart, which is called the epicardial potential distribution, is a valuable tool to understand whether there is a defect in the heart. Direct measurement of these potentials requires highly invasive procedures. An alternative is to reconstruct these epicardial potentials non-invasively from the body surface potentials, which constitutes... View full abstract»

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  • Toward effective medical search engines

    Publication Year: 2010, Page(s):21 - 26
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (165 KB) | HTML iconHTML

    In this paper, we present a domain specific search engine that relies on extracting the semantic relation among medical documents. Our goal is to maximize the contextual retrieval and ranking performance with minimum input from users. We have performed experiments to measure the effectiveness of the proposed technique by evaluating the performance of the retrieval process in terms of recall, preci... View full abstract»

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  • Physico-chemical properties of DNA in phylogeny construction

    Publication Year: 2010, Page(s):27 - 30
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (340 KB) | HTML iconHTML

    Phylogenic analysis relies on alignment of related sequences from different species to obtain the distances between these species. The quality of the alignment and the distance measure would depend on the alignment parameters that are used. In this work, we propose to use Relative Complexity Measure (RCM) to find the distances between the sequences which is not a parameter dependent measure. We us... View full abstract»

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  • Systematic computational analysis of potential RNAi regulation in Toxoplasma gondii

    Publication Year: 2010, Page(s):31 - 38
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (420 KB) | HTML iconHTML

    RNA interference (RNAi) is the mechanism through which RNA interferes with the production of other RNAs in a sequence specific manner. Micro RNA (miRNA) is a type of RNA which is transcribed as pri-miRNAs and processed to pre-miRNAs in the nucleus. These pre-miRNAs are then exported from the nucleus and processed in the cytoplasm to double stranded RNA with one strand providing target specificity.... View full abstract»

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  • Multiple sequence alignment based on structural properties

    Publication Year: 2010, Page(s):39 - 44
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1954 KB) | HTML iconHTML

    A multiple sequence alignment (MSA) is a sequence alignment of three or more biological sequences. Main idea behind multiple sequence alignment is to see the similarities between input sequences, to be able to make phylogenetic analysis and other evolutionary conclusions. We propose a multiple sequence alignment method based on contact maps derived from structural data and network properties. We s... View full abstract»

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  • A zero-norm feature selection method for improving the performance of the one-class machine learning for microRNA target detection

    Publication Year: 2010, Page(s):45 - 50
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (128 KB)

    The application of one-class machine learning is gaining attention in the computational biology community. Different studies have described the use of two-class machine learning to predict microRNAs (miRNAs) gene target. Most of these methods require the generation of an artificial negative class. However, designation of the negative class can be problematic and if it is not properly done can affe... View full abstract»

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  • Supervising Event Executive

    Publication Year: 2010, Page(s):51 - 55
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (301 KB) | HTML iconHTML

    There are many advances in nurse-call devices but there is a lack of proper integration and interoperation among them. This paper presents a software application to join these devices together in a LAN environment such as Hospital Information System. This software application is called Supervising Event Executive (SEE) that is developed to provide a common, convenient, and reliable means of transf... View full abstract»

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  • Turkish Aeromedical Center

    Publication Year: 2010, Page(s):56 - 58
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (135 KB) | HTML iconHTML

    Eskisehir Military Hospital makes aircrew's periodic health examinations annually and five yearly. And Aircrew's Health Research and Training Center give physiological trainings to aircrew five yearly. Physiological Training is necessary, because; pilots who are knowledgeable about physiological phenomena encountered in the aviation environment are better prepared to deal with such potentially fat... View full abstract»

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  • Behavioural intension analysis of Avicenna® Hospital Information System

    Publication Year: 2010, Page(s):59 - 66
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (288 KB) | HTML iconHTML

    "Hospital Information Systems" are designed for improving the health quality of people and for the management of all the hospital's medical and administrative information in order to enable health professionals to perform their jobs effectively and efficiency. However the main problem has been raising that is whether hospital personnel want to use these systems while performing their tasks. This s... View full abstract»

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  • The clinical guidelines usage towards the diagnosis and treatment of H1N1

    Publication Year: 2010, Page(s):67 - 71
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (87 KB) | HTML iconHTML

    In medical clinics, guidelines are the best ways for practitioners to make good decisions on patient's medical problems. There are different kinds of symptoms at all kinds of illnesses and this will affect the medicians' decision on the diagnosis/treatment. These guidelines are the results of an algorithm to follow and the ways to defeat the illness. These guidelines are developed in textual forma... View full abstract»

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  • Inhibitor peptide design for NF-кB: Markov model & genetic algorithm

    Publication Year: 2010, Page(s):72 - 80
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (709 KB) | HTML iconHTML

    Two peptide design approaches are proposed to block activities of disease related proteins. First approach employs a probabilistic method; the problem is set as Markov chain. The possible binding site of target protein and a path on this binding site are determined. 20 natural amino acids and 400 dipeptides are docked to the selected path using the AutoDock software. The statistical weight matrice... View full abstract»

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  • Computational analysis of the binding free energy of H3K9me3 peptide to the tandem tudor domains of JMJD2A

    Publication Year: 2010, Page(s):81 - 87
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (408 KB) | HTML iconHTML

    JMJD2A is a histone lysine demethylase enzyme which plays a prominent role in the development of prostate and esophageal squamous cancers. Consisting of a JmjC, a JmjN, two PHD and two tandem tudor domains, JMJD2A recognizes and binds to four different methylated histone peptides: H3K4me3, H4K20me3, H4K20me2 and H3K9me3, via its tudor domains. Of the four histone peptides, only recognition of the ... View full abstract»

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  • Relation between kinetic conversion rates and ANM mode frequencies

    Publication Year: 2010, Page(s):88 - 92
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (111 KB) | HTML iconHTML

    Elastic Network Models (ENMs) are informative, fast and largely used techniques for the elucidation of the intrinsic motions of the proteins. ENM normal modes resemble the conformational changes in the ligand-free states of the proteins. According to pre-existing equilibrium model the native state of the protein forms an ensemble of substates and ligand simply selects and shifts the population dyn... View full abstract»

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  • SUMOtr: SUMOylation site prediction based on 3D structure and hydrophobicity

    Publication Year: 2010, Page(s):93 - 97
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (263 KB) | HTML iconHTML

    A post translational modification SUMOylation is one of the vital processes of protein maturation and function. Determining a protein's SUMOylation status is important in the context of determining that protein's function, nuclear localization, and intra-nuclear spatial association. Many of the predictors currently use a consensus motif, which is ΨKxE (where Ψ is a large aliphatic br... View full abstract»

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  • Classification of EEG signals in four groups, including healthy subjects with open/closed eyes and epilepsy subjects with/without seizure by PSD estimate (using the multitaper method) and ANN

    Publication Year: 2010, Page(s):98 - 103
    Cited by:  Papers (2)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (346 KB) | HTML iconHTML

    Electroencephalography (EEG) analysis by physicians is intricate, time consuming and needs to experience. Therefore automated systems for EEG analysis and classification are able to help physician. EEG signal in the field of time is raw and complex so it's not suitable for automated system. Therefore appropriate features of EEG signal becomes extraction using signal processing methods (in this pap... View full abstract»

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  • Computer aided diagnosis for spina bifida

    Publication Year: 2010, Page(s):104 - 109
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (338 KB) | HTML iconHTML

    This article addresses one of a wide range of computer aided detection/diagnosis (CAD) problems. Specifically, our aim is to detect the relatively common spina bifida pathology in the prenatal period exploiting fetal ultrasound images. Among many potential ways to perform such detections, we work with transcerebellar brain images of the fetus and search for the presence of an indicative marker of ... View full abstract»

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  • Classification of normal and abnormal respiration patterns using flow volume curve and neural network

    Publication Year: 2010, Page(s):110 - 113
    Cited by:  Papers (5)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (244 KB) | HTML iconHTML

    Lung diseases affect many people's lives. Early and correct diagnosis of respiratory system abnormalities is vital to patients. While spirometry is the most common pulmonary function test, the interpretation of the results is dependent on the physicians' experience. A decision support system can help physicians in correct diagnoses. This study aims at designing a system for detecting pulmonary sys... View full abstract»

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  • Machine learning techniques to diagnose breast cancer

    Publication Year: 2010, Page(s):114 - 120
    Cited by:  Papers (3)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (209 KB) | HTML iconHTML

    Machine learning is a branch of artificial intelligence that employs a variety of statistical, probabilistic and optimization techniques that allows computers to “learn” from past examples and to detect hard-to-discern patterns from large, noisy or complex data sets. As a result, machine learning is frequently used in cancer diagnosis and detection. In this paper, support vector mach... View full abstract»

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