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Biophotonics, Nanophotonics and Metamaterials, 2006. Metamaterials 2006. International Symposium on

Date 16-18 Oct. 2006

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Displaying Results 1 - 25 of 166
  • [Front cover]

    Publication Year: 2006 , Page(s): C1
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  • Copyright page

    Publication Year: 2006 , Page(s): nil1
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  • Conference committee

    Publication Year: 2006 , Page(s): nil2
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  • Technical Program Committee

    Publication Year: 2006 , Page(s): nil3
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  • Foreword

    Publication Year: 2006 , Page(s): I - II
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  • Table of contents

    Publication Year: 2006 , Page(s): III - XIV
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  • Biophotonics Session

    Publication Year: 2006 , Page(s): 1
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  • Highly Sensitive Photonic Biosensors Based on Interferometric Detection of Surface Plasmon Waves

    Publication Year: 2006
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    Summary form only given. We previously demonstrated an interferometric surface plasmon resonance (SPR) biosensor design based on measuring the differential phase between the s- and p-polarization. In this presentation, we report our recent results on the development of sensor arrays achieved by analyzing interferograms generated under SPR conditions. The measurement approach has the merits of performing highly paralleled two-dimensional detection at fixed angle of incidence. In addition, we also demonstrate further improvement of detection resolution (in the order of 10-8 RIU) by incorporating novel ideas in the design of the optical interferometer. View full abstract»

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  • Multiple Photonic Responses in Organic Magnetic Semiconductor V(TCNE)x(x ~ 2)

    Publication Year: 2006
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    A multiphotonic response in organic magnetic semiconductor V(TCNE)x (x ~ 2) with a substantial increase of conductivity induced by light (lambda=457.9 nm) is reported. Substantial decrease in activation energy for electronic hopping is due to temperature dependence of resistivity. Photoinduced effects that originated from structural changes triggered by pirarrpi* excitation in (TCNE)ldr- molecules, which leads to modulation of the magnetic exchange energy J and the activation energy DeltaE, is proposed. This mechanism for multiphotonic responses is supported by photoinduced IR studies. View full abstract»

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  • Detection of epithelial structure and biochemistry based on time-resolved confocal autofluorescence

    Publication Year: 2006 , Page(s): 4 - 7
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    A combined depth- and time-resolved fluorescence measurement system with ultraviolet excitation at 375 nm is built to assess the layered structure and biochemistry of epithelial tissue. The experiments on epithelial cells suggested that the time-resolved autofluorescence dominated by free/bound NADH signals, are sensitive indicators for cell metabolism and can be used to sense the metabolic status of epithelial tissue. Moreover, we found that the fluorescence time decays of different epithelial tissue layers can produce the contrast to resolve the tissue fine structure. This study demonstrated that the combined depth- and time-resolved autofluorescence measurements with single excitation at 375 nm can potentially provide accurate information for the diagnosis of tissue pathology. View full abstract»

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  • Improvement of Spatial Resolution in Two-Photon Stereolithography

    Publication Year: 2006 , Page(s): 8 - 14
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (7978 KB) |  | HTML iconHTML  

    Two-photon stereolithography based on photopolymerization provides the ability to fabricate real three- dimensional (3D) microstructures beyond the resolution of focal size. In this paper, our recent research focusing on improvement of spatial resolution in two-photon stereolithography is reviewed. The influence of system and fabrication conditions in relation to the spatial resolution is discussed. For small and low aspect ratio voxels, a minimum power and minimum exposure time (MPMT) scheme is introduced. During the two-photon process, an ascending technique, wherein the truncation amount of volumetric pixels is controlled, can be applied to improve the resolution of two-dimensional patterns. 3D microfabrication with less than 100 nm resolution can be realized by using the radical quenching effect. After the two-photon process, the resolution of fabricated patterns can be refined to 60 nm by post-processing of plasma ashing. View full abstract»

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  • Silicon Microphotonic Waveguides for Biological Sensing

    Publication Year: 2006 , Page(s): 15 - 18
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (3823 KB) |  | HTML iconHTML  

    The advantages of the silicon-on-insulator (SOI) waveguide platform are examined for evanescent field (EF) based biological sensing. It is suggested that the high index contrast (HIC) inherent to SOI waveguides allows sensors fabricated in this material to demonstrate improved sensitivity over that of all other common planar waveguide platforms for the probing of thin biological layers. View full abstract»

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  • Polymerized Crystalline Colloidal Array Photonic Crystals for Chemical Sensing and Optoelectronics

    Publication Year: 2006
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    We have developed a novel class of smart optical materials based on soft materials which are responsive to their environment and which can be actuated chemically or photonically. Highly charged, monodisperse colloidal particles will self assemble in water into crystalline colloidal arrays (CCA), which are either body centered or face centered cubic structures. We have developed smart materials from these self-assembled structures, which utilize the highly efficient Bragg diffraction of light from the CCA periodicity. We polymerized these CCA into acrylamide hydrogels. These CCA-embedded hydrogels show the rich volume phase transition phenomena characteristic of these soft materials. These materials act as frequency agile optical filters. We have functionalized these hydrogels with dyes and photochromic molecules, as well as with molecular recognition agents which cause the hydrogel to change volume in response to either photons, or the presence of specific analytes (eg Pb2+, glucose etc). The resulting volume changes alter the array spacing, which causes the diffracted light wavelength to shift, or causes the diffraction efficiency to change. We will discuss the volume phase transition properties of these arrays and also describe the use of these arrays and also describe the use of these arrays and also describe the use of these arrays as chemical sensors, novel ns optical switching materials as well as optical memory devices. View full abstract»

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  • DNA, nanoparticles and photons - new approaches for clinical diagnostics

    Publication Year: 2006
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    The main motivation of this paper is to create new bioanalytical tools integrated within photonic and MEMS platforms. These technologies are being developed for bioassays not currently possible by using other approaches and include methods for the analysis of long DNA fragments in low copy number. In the development of these approaches, new self-assembly nanobiomaterial fabrication methods are described and discussed. View full abstract»

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  • Introduction to Nanobiophotonics

    Publication Year: 2006 , Page(s): 22
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (603 KB) |  | HTML iconHTML  

    Nanobiophotonics is combination of nanotechnology and biotechnology with photonics. The basic principles and new advances in nanophotonics probes for biomedical technology and challenges in this field are presented. Bioimaging and biosensing using nanoprobes to study cellular and tissue interactions, control of excited state dynamics for photodynamic therapy, and nanocontrol dynamics in fluorescence resonance energy transfer for real time monitoring and drug delivery, as examples, are also discussed. View full abstract»

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  • Optical Fluorescence Imaging of Breast Cancer

    Publication Year: 2006 , Page(s): 23 - 25
    Cited by:  Papers (2)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (3086 KB) |  | HTML iconHTML  

    We report on the first results obtained with the Philips diffuse optical tomography system and Schering AG's Omocianine fluorescent dye. View full abstract»

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  • Modeling of multi-photon-induced photoluminescence from organic fluorophores and metal-coated semiconductor nanoparticles

    Publication Year: 2006
    Cited by:  Patents (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (675 KB)  

    In this talk I will describe some applications of multiphysics modeling of molecular and nano-particle materials that have been carried out at our department. Among the various multiphysics approaches, those that combine quantum mechanics with wave mechanics and quantum mechanics with statistical mechanics have turned out to be particularly powerful for predicting optical properties of organic fluorophores, respectively, nanoparticles. The first type of combined approach allows to estimate the optical transmission from cross sections of multi-photon absorption processes and from considerations of propagation and saturation effects. The other type of combined approach, quantum mechanics with statistical mechanics, allows to account for the spontaneous photon emission of two-photon excited quantum dots including the nonradiative energy dissipation process of phonon scattering. Multi-photon quantum dots offer the combined advantage of brilliance and photo- resistance of normal quantum dots with the 3-dimensional confocality and penetration of multi-photon excitation, something that can have a broad ramification on fluorescence based experiments in biology. We have in particular investigated multiphoton-induced photoluminescence from metal-coated coated quantum dots under the influence of electromagnetic field enhancement associated with surface plasmon resonances. It is argued that up-conversion luminescence of coated quantum dots is a promising approach for bio-imaging as it can generate the multiphoton excitation at reduced laser intensities. View full abstract»

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  • Photobiomodulation of Diagnostic Monochromatic Light or Laser Irradiation

    Publication Year: 2006 , Page(s): 27 - 30
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (242 KB) |  | HTML iconHTML  

    Low intensity monochromatic light or laser irradiation (LIL) has been widely used to diagnose biosystems, but the photobiomodulation (PBM) of LIL on the diagnostic biosystems was not always considered. PBM and its mechanism have been deeply studied. In this paper, PBM mechanism is used to study the PBM of diagnostic LIL (DPBM) so that the affection of DPBM can be really ignored. View full abstract»

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  • Intramolecular energy transfer in a two-photon absorbing naphtahlimide-triphenylamine dyad

    Publication Year: 2006 , Page(s): 31 - 33
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (257 KB) |  | HTML iconHTML  

    When a triphenylamine (TPA) is incorporated to a fluorephore of 2-Ethyl-6-(1-piperidinyl)-1H-benz[de]isoquinoline-1,3(2H dione (EPQD), energy absorbed by EPQD unit will mostly transfer to TPA unit inside the new molecule 2-(4-Diphenylamino-phenyl)-6-(1-piperidinyl)-1H-benz[de]isoquinoline-1,3(2H)-dione (APQD) through electron transfer, and then relax with no fluorescence. APQD, whose fluorescence quenched by the intramolecular energy transfer, has a little larger two-photon absorption cross-section than its reference dye EPQD. View full abstract»

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  • Noninvasive and Real-time Monitoring of the Regulation of Plant Growth and Development Using Delayed Fluorescence Technique

    Publication Year: 2006 , Page(s): 38 - 41
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (207 KB) |  | HTML iconHTML  

    The structure and function of photosynthetic apparatus in plant leaves can be affected by plant growth regulators (PGRs) and other exogenous chemical factors. The photosystem II in a plant is considered the primary site where light-induced delayed fluorescence (DF) is produced. With the lamina of soybean (Glycine max (L.) Merr.) seedlings as testing models, we have studied the effects of sodium bisulfite (NaHSO3) on characteristics of DF using a home-made portable DF detection system. The results show that the changes in DF intensity can reflect the changes in photosynthetic capacity caused by NaHSO3. Therefore, the light-induced DF is a novel and excellent marker for early and rapidly detecting the regulatory effects of NaHSO3 on plant photosynthetic metabolism. DF technique could be potential useful for real-time monitoring the effects of PGRs and other exogenous chemical factors on plant growth and development. View full abstract»

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  • Characterization of Target effect of Nano-hydrogel by Near-infrared Fluorescent Quantum Dots

    Publication Year: 2006 , Page(s): 42 - 45
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (304 KB) |  | HTML iconHTML  

    Nano-hydrogel is one of the most promising drug carrier for its sensitivity to environmental stimulus. For in vivo optical imaging of nano-hydrogel, the development of novel contrast agents with near-infrared (NIR) fluorescence is especially important. Poly-N-isopropylacrylamide-co-acrylic acid (PNIPA-co-AA) nano-hydrogel was synthesized by precipitation polymerization method. The regulation on the size and lower critical solution temperature (LCST) of the hydrogel nanoparticles were intensively studied. Semiconductor nanocrystals CdHgTe were grown in aqueous solution and then labeled PNIPA-co-AA. PNIPA-co-AA nano-hydrogel has a least diameter distribution around 50 nm and a tunable lower critical solution temperature (LCST) from 35 to 45degC, which made it to have site-specific effect. The nanocrystals were approximately 5 nm in diameter and have a broad fluorescence peak in the NIR spectra range (750 nm). Nanocrystals CdHgTe coated PNIPA-co-AA has good NIR fluorescence sensitivity. The NIR fluorescence of the nanocrystals together with the target effect of PNIPA-co-AA makes them particularly attractive candidates for in vivo imaging and drug pharmacokinetics studies. View full abstract»

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  • Studies of Free Gas in Scattering Media at Micro- and Macroscopic Scales

    Publication Year: 2006 , Page(s): 46 - 49
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (339 KB) |  | HTML iconHTML  

    Free gases in scattering media and different techniques for such studies are discussed in the present paper. Connections between two techniques that constitute a major research area at our laboratory are presented. One of the techniques concerns measurements of free gas in scattering media, such as human tissue and food products, on a small scale, while the other one is a technique for trace-gas measurements in the lower atmosphere. We show that the basic ideas are very similar and that, by applying the knowledge obtained on one scale to the other, little differences exist. This study motivates us to perform a measurement linking the two techniques. View full abstract»

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  • Layer Structures Localization in Optical Coherence Tomography Images

    Publication Year: 2006 , Page(s): 50 - 53
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (514 KB) |  | HTML iconHTML  

    The existence of noise and speckle in optical coherence tomography (OCT) images challenges the extraction of layer structures. As an effort to answer the challenges, an improved coherence enhancing diffusion (CED) algorithm for preprocessing OCT images is presented in this paper. The improved algorithm could keep the locality of layer structures in OCT images better, therefore, locality of layer structures could be detected with good accuracy in preprocessed OCT images. The locality of some specific layer structures found in preprocessed images could be used as the benchmark to optimize OCT images, the application in OCT images of retina is such an example. Experiment results show that the above optimization is clinical helpful. View full abstract»

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  • Infrared Spectrum Visualizing Human Acupoints and Meridian-like Structure

    Publication Year: 2006 , Page(s): 54 - 56
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (373 KB) |  | HTML iconHTML  

    This study investigates the infrared radiant characteristics of human acupoints and meridian-like structure by use of infrared thermal imaging. Thirty healthy youth volunteers are studied in our experiment. We find that human acupoints and meridian-like structure can be visualized or revealed in the infrared spectrum range in some of them under natural condition. The infrared radiant tracks of meridian courses over body surface coincide or basically coincide with that of human meridians described by the traditional Chinese medicine textbook. The facts show evidence for the objective existence of acupuncture meridians structure in human body. The results suggest that infrared radiant track along human meridian courses is a normal vital and physiological phenomenon appearing in human being. View full abstract»

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  • On-spot Evaluation of Maturity Stage of Fruits Based on 655 nm Laser-induced Photoluminescence of Chlorophyll-α

    Publication Year: 2006 , Page(s): 57 - 59
    Cited by:  Papers (1)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (198 KB) |  | HTML iconHTML  

    A technique to evaluate maturity stage of fruits, measured nondestructively and in situ by laser-induced photoluminescence of chlorophyll-α, was successfully developed. Using 655 nm laser diode as a new kind of light source to stimulate fluorescence as well as combining fiber and spectrum technique, various spectrums from 500 to 900 nm were recorded for different ripening stages of fruits. Experiments revealed that the content of chlorophyll-α decreases significantly with the fruit ripening. This method is completely feasible to give a visual judgment for chlorophyll-α content, according to the fluorescence emission spectrum of chlorophyll-α, and can be applied in a conveyor belt system using sorting criteria such as concentration of the chlorophyll-α. View full abstract»

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