Measuring the cortical thickness [MRI segmentation procedure]
Kruggel, F.
Yves von Cramon, D.
Max-Planck-Inst. of Cognitive Neurosci., Leipzig ;
This paper appears in: Mathematical Methods in Biomedical Image Analysis, 2000. Proceedings. IEEE Workshop on
Publication Date: 2000
On page(s): 154-161
Meeting Date: 06/11/2000 - 06/12/2000
Location: Hilton Head Island, SC, USA
ISBN: 0-7695-0737-9
References Cited: 23
INSPEC Accession Number: 6657275
Digital Object Identifier: 10.1109/MMBIA.2000.852372
Current Version Published: 2002-08-06
Abstract
Besides normal aging, a number of brain diseases are known to
reduce the amount of grey matter in the brain. To better understand the
nature and progression of these disease processes, quantitative
measurements of relevant brain structures, such as the regional cortical
thickness, are highly desirable. Starting from high resolution
volumetric MR images of the human head, a reliable segmentation
procedure for the grey matter compartment is described which allows
thickness measurements at sub-voxel resolution. Simulation experiments
and comparisons with published data from histological examinations prove
the validity of results
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