System-on-chip ultrasonic transducer for dental tissue formation and stem cell growth and differentiation
Woon Tiong Ang
Changhong Yif
Jie Chen
El-Bialy, T.
Doschak, M.
Uludag, H.
Ying Tsui
Electr. & Comput. Eng. Dept., Univ. of Alberta, Edmonton, AB;
This paper appears in: Circuits and Systems, 2008. ISCAS 2008. IEEE International Symposium on
Publication Date: 18-21 May 2008
On page(s): 1818-1821
Location: Seattle, WA,
ISBN: 978-1-4244-1683-7
INSPEC Accession Number: 10048847
Digital Object Identifier: 10.1109/ISCAS.2008.4541793
Current Version Published: 2008-06-13
Abstract
Conventional ultrasound designs are used for medical therapeutics including different tissue healing and medical imaging. Recently, we discovered that the low intensity pulsed ultrasound (LIPUS) can help stimulate dental and bone tissue growth. However, the size of available ultrasound devices is too large to fit inside the mouth.,. In this paper, we present the design of a system-on-chip ultrasonic device for dental tissue formation and stem cell growth differentiation. The device helps tissue healing by stimulating formation of new blood vessels and different tissue matrix formation, like bone, dentin and cementum. Testing results show that our prototype device can stimulate stem cells to grow and differentiate into bone forming cells.
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