Examining coding structure and redundancy in DNA
Rosen, G.
Center for Signal & Image Process., Georgia Inst. of Technol., Atlanta, GA, USA;
This paper appears in: Engineering in Medicine and Biology Magazine, IEEE
Publication Date: Jan.-Feb. 2006
Volume: 25,
Issue: 1
On page(s): 62-68
ISSN: 0739-5175
INSPEC Accession Number: 8765490
Digital Object Identifier: 10.1109/MEMB.2006.1578665
Current Version Published: 2006-01-23
Abstract
A review of DNA signal content, redundancy, and mutational mechanisms is presented. Mutation-robust methods are developed to detect a linear coding structure and approximate tandem repeats. In this article, a method to uncover an error-correction coding structure in the nucleotide sequence is developed and its efficiency in detecting approximate tandem repeats, such as microsatellite regions, is demonstrated.
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