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Artificial neural networks are considered good alternatives to conventional statistical methods for the prediction of survival. Neural networks have been used in medicine since the late 1980s, first, as an aid to diagnosis and treatment and then, recently, as a tool to study medical prognosis of a variety of diseases. Survival predictions at the individual level can help patients make informed decisions with regards to the quality of life and finance. We describe our research in the use of neural network to predict the prognosis of nasopharyngeal carcinoma. Two prognostic models for nasopharyngeal carcinoma were developed, namely the multi-layer perceptron model and the recurrent model and their performance compared.