A pulsed source-sink fluid mixing device
Cola, B.A.
Schaffer, D.K.
Fisher, T.S.
Stremler, M.A.
Dept. of Mech. Eng., Vanderbilt Univ., Nashville, TN, USA;
This paper appears in: Microelectromechanical Systems, Journal of
Publication Date: Feb. 2006
Volume: 15,
Issue: 1
On page(s): 259- 266
ISSN: 1057-7157
INSPEC Accession Number: 8771691
Digital Object Identifier: 10.1109/JMEMS.2005.863786
Current Version Published: 2006-02-06
Abstract
Efficient fluid mixing can be achieved in a high-aspect-ratio volume by periodically pulsing an arrangement of source-sink pairs. In order to conserve fluid and promote mixing, the fluid extracted through a sink is subsequently injected through a source. We present an implementation of this approach that consists of a disposable chip with embedded microchannels and external fluidic control. When both the mixing chamber geometry and the source-sink arrangement are fixed, mixing is controlled by choosing α, the fraction of the mixing chamber volume that is exchanged with each pulse. Experimental results in a rectangular chamber show that the value of α has a significant effect on mixing efficiency. This device shows promise for enhancing the performance of massively parallel sensing systems such as DNA microarrays.
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