Structure and stability of certain chemical networks andapplications to the kinetic proofreading model of T-cell receptor signaltransduction
Sontag, E.D.
Dept. of Math., Rutgers Univ., New Brunswick, NJ ;
This paper appears in: Automatic Control, IEEE Transactions on
Publication Date: Jul 2001
Volume: 46,
Issue: 7
On page(s): 1028-1047
ISSN: 0018-9286
References Cited: 25
CODEN: IETAA9
INSPEC Accession Number: 6994780
Digital Object Identifier: 10.1109/9.935056
Current Version Published: 2002-08-07
Abstract
Deals with the theory of structure, stability, robustness, and
stabilization for an appealing class of nonlinear systems which arises
in the analysis of chemical networks. The results given here extend, but
are also heavily based upon, certain previous work by Feinberg (1977,
1979, 1987, 1995) and Horn and Jackson (1972), of which a self-contained
and streamlined exposition is included. The theoretical conclusions are
illustrated through an application to the kinetic proofreading model
proposed by McKeithan (1995) for T-cell receptor signal transduction
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