Overcoming the screening-induced performance limits of nanowire biosensors: A simulation study on the effect of electro-diffusion flow
Yang Liu
Lilja, K.
Heitzinger, C.
Dutton, R.W.
Center for Integrated Syst., Stanford Univ., Stanford, CA;
This paper appears in: Electron Devices Meeting, 2008. IEDM 2008. IEEE International
Publication Date: 15-17 Dec. 2008
On page(s): 1-4
Location: San Francisco, CA,
ISSN: 8164-2284
ISBN: 978-1-4244-2377-4
INSPEC Accession Number: 10500572
Digital Object Identifier: 10.1109/IEDM.2008.4796733
Current Version Published: 2009-02-27
Abstract
Device-level simulation capabilities have been developed to self-consistently model the Si-nanowire (NW) biosensor systems. Our numerical study demonstrates that by introducing electro-diffusion current flow in the electrolyte solutions, the electrostatic screening of the biological charge can be significantly suppressed; an improvement of the sensed signal strength by >ap10X is indicated. Based on such an operation principle, the screening-induced performance limits on Si-NW biosensors can be overcome.
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