Noninvasive Imaging of Bioimpedance Distribution by Means of Current Reconstruction Magnetic Resonance Electrical Impedance Tomography
Nuo Gao
Bin He
Univ. of Minnesota, Minneapolis;
This paper appears in: Biomedical Engineering, IEEE Transactions on
Publication Date: May 2008
Volume: 55,
Issue: 5
On page(s): 1530-1538
ISSN: 0018-9294
INSPEC Accession Number: 9921379
Digital Object Identifier: 10.1109/TBME.2008.918565
Current Version Published: 2008-04-15
Abstract
We have developed a novel magnetic resonance electrical impedance tomography (MREIT) algorithm-current reconstruction MREIT algorithm-for noninvasive imaging of electrical impedance distribution of a biological system using only one component of magnetic flux density. The newly proposed algorithm uses the inverse of Biot-Savart Law to reconstruct the current density distribution, and then, uses a modified J-substitution algorithm to reconstruct the conductivity image. A series of computer simulations has been conducted to evaluate the performance of the proposed current reconstruction MREIT algorithm with simulation settings for breast cancer imaging applications, with consideration of measurement noise, current injection strength, size of simulated tumors, spatial resolution, and position dependency. The present simulation results are highly promising, demonstrating the high spatial resolution, high accuracy in conductivity reconstruction, and robustness against noise of the proposed algorithm for imaging electrical impedance of a biological system. The present MREIT method may have potential applications to breast cancer imaging and imaging of other organs.
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