Computational methods for predicting intramolecular G-quadruplexes in nucleotide sequences
D'Antonio, L.
Bagga, P.
Dept. of Comput. Sci., Ramapo Coll. of New Jersey, Mahwah, NJ, USA;
Abstract
Guanine-rich sequences, including those that form G-quadruplexes, are abundant in regions of biological significance. In order to map putative G-quadruplex elements within mammalian genes we have created a suite of computational tools. This suite contains algorithms to search genes for occurrences of the G-quadruplex motif and determine their distribution near RNA processing sites.
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