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Introduction to Tissue Engineering:Applications and Challenges

Cover Image Copyright Year: 2014
Author(s): Ravi Birla
Publisher: Wiley-IEEE Press
Content Type : Books & eBooks
Topics: Bioengineering ;  Computing & Processing
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      FrontMatter

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      This chapter contains sections titled:
      Half-Title
      Series Page
      Title
      Copyright
      Dedication
      Contents
      Preface
      Acknowledgments
      List of Abbreviations
      Important Terminology and Concepts View full abstract»

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      Introduction to Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      In this chapter we introduce the field of tissue engineering and provide a working definition for tissue engineering. We describe seminal publications in the field and look at closely related fields like cell transplantation, regenerative medicine and reparative. We describe the building blocks of tissue engineering, which include cells, biomaterials and bioreactors. We provide an eight step process for tissue and organ fabrication and discuss scientific and technological challenges in the field. We describe the collaborative research for tissue engineering and discuss drivers for growth in the field. View full abstract»

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      Cells for Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      Cells provide the functional component of artificial tissue and organs and in this chapter, we introduce the concept of cells at it applies to the tissue and organ fabrication process. We begin with an introduction to cell biology and discuss cell-cell and cell-matrix interactions. We also describe cellular signaling and discuss the structure and function of cellular junctions. We describe the cell culture process and explain different stages of cell culture and expansion. During the course of this chapter, we provide a description of cell transplantation and the use of stem cells for tissue engineering and cell therapy. View full abstract»

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      Biomaterials for Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      Biomaterials are used to provide structural support during the tissue and organ fabrication process and are designed to simulate properties of the mammalian extracellular matrix. In this chapter, we provide a broad overview of biomaterials as they apply to tissue engineering. We provide a working definition of biomaterials and discuss biomaterial classification schemes and biomaterial platforms. During the course of this chapter, we also study biomaterial properties, including tensile properties, degradation kinetics, biocompatibility and biomimetic properties. View full abstract»

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      Tissue Fabrication Technology

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      In this chapter, we describe current state of the art to support tissue and organ fabrication. We describe several technologies, some of which self-organization technology and cell sheet engineering. We also describe cell and organ printing as it applies to tissue engineering. Scaffold based tissue engineering approaches are also described. During the course of this chapter we also introduce the concepts of soft-lithography, micro-fluidics and organ-on-a-chip models. View full abstract»

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      Vascularization of Artificial Tissue

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      We introduce the concept of vascularization as it applies to the tissue and organ fabrication process. We describe molecular mechanisms of several vascularization process, including vasculogenesis, angiogenesis, and arteriogenesis and discuss the application of these process to the tissue fabrication process. We provide a framework for vascularization of 3D artificial tissue and organs, including biologically replicated, biologically inspired, and biologically replicated models. View full abstract»

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      Bioreactors for Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      We introduce the concept of bioreactors as applied to the tissue and organ fabrication process. We begin by providing a framework for bioreactors, provide a definition and describe a classification for bioreactors. We provide specific examples of bioreactors for cell culture, biomaterial synthesis, scaffold cellularization, mechanical stretch, electrical stimulation and perfusion. View full abstract»

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      Tracheal Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      We provide a description of the structure and function of the mammalian trachea. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the trachea. View full abstract»

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      Bladder Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      We provide a description of the structure and function of the mammalian bladder. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the bladder. View full abstract»

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      Liver Tissue Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      We provide a description of the structure and function of the mammalian liver. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the liver. View full abstract»

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      Index

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

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      IEEE Press Series in Biomedical Engineering

      Copyright Year: 2014

      Wiley-IEEE Press eBook Chapters

      No abstract. View full abstract»