Development of electronic nose for diagnosis of lung cancer at early atage

In this paper, we proposed a novel non-invasive electronic nose for detection and diagnosis of lung cancer based on an electronic nose instrument which includes a gas extraction and capillary column to concentrate, desorb and separate volatile organic compounds (VOCs) in patients’ breath, respectively. Surface Acoustic Wave (SAW) gas sensors was used to detect chemical compounds. The specific VOCs exhaled by lung cancer cells in the microenvironment are proven the source biomarkers of lung cancer. The clinical experimental results show that this kind of novel electronic nose is effective for recognition of lung cancer patents and healthy persons and will be also possible non-invasive method to diagnose of lung cancer at early stage.