This study investigates whether microfabricated silicon-based biocapsules, with uniform membrane pore sizes in the tens of nanometer range, can provide immunoprotection of rat islets transplanted into a mouse model. By utilizing microfabrication technology, biocapsules are fabricated with membranes having precisely controlled and uniform pore sizes, allowing one to optimize parameters specifically for the immunoisolation of hormone-secreting cells. The study evaluates biocompatibility and short term therapeutic efficacy for implanted biocapsules
Published in:
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
(Volume:2
)
Date of Conference: Oct 1999