Raman spectroscopy for cancer detection: a review

This article reviews recent developments in the attempt to develop diagnostic techniques for cancers and precancers based on Raman spectroscopy. The article summarizes some facts about cancer biology as it pertains to Raman diagnosis. It reviews certain instrumentation considerations and finally surveys the application of Raman spectroscopy for diagnosis on intact tissues. The article concludes with our perspective on the current status of Raman spectroscopy for clinical applications and its future.