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Magnetic Nanoparticles for Therapy and Diagnostics

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6 Author(s)
Pollert, E. ; Inst. of Phys., Prague, Czech Republic ; Kaspar, P. ; Zaveta, K. ; Herynek, V.
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The research and utilization of the magnetic nanoparticles in, e.g., biology and medicine have been preferentially oriented on magnetite Fe3O4 and maghemite γ-Fe2O3. The complex oxides allow a better control of the magnetic properties in a desirable way. We demonstrate this approach on an example of the La1-xSrxMnO3 perovskites from the point of view of their use in self-controlled magnetic fluid hyperthermia and increase of contrast in magnetic resonance imaging. With materials possessing suitable values of transition temperature TC, coercivity and magnetization, the heating power generated by the nanoparticles was estimated by two independent methods and they were finally employed in vitro and in vivo hyperthermia experiments.

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Magnetics, IEEE Transactions on  (Volume:49 ,  Issue: 1 )