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Artificial Life has been an inspiration for Virtual Reality Art, which has proposed the design of imaginary life forms and has also used Artificial Life techniques in various installations. The creation of imaginary life forms has been so far limited to the external appearance of these creatures. We introduce a novel approach to the design of artificial life forms, which enables the description of their internal physiology from first principles, by using a simulation method known as qualitative physiology, derived from a well described Artificial Intelligence technique. We illustrate this framework by revisiting early work in Artificial Life and providing these virtual life forms with a corresponding physiology, so as to obtain complete living organism in virtual worlds.