By Topic

Beyond Watson and Crick: Programming DNA self-assembly for nanofabrication

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

1 Author(s)
Paul W. K. Rothemund ; Department of Bioengineering, California Institute of Technology, USA

The specificity of Watson-Crick base-pairing allows great control over the design and synthesis of artificial DNA nanostructures. Periodic one-dimensional (1D) tubes, 2D lattices, and 3D crystals are easily created from “DNA tiles” with spacings of 10-20 nanometers. “DNA origami” allows the folding of long DNA strands into arbitrary shapes and patterns up to about 100 nanometers in size with five nanometer features. This suggests that DNA self-assembly might be used for sublithographic fabrication of devices or even circuits. There are, however, a number of challenges. For example, compared to the inorganic materials used as semiconductors, DNA has poor electronic properties and must be augmented by other materials. Such challenges must be solved before DNA self-assembly can be used in a complete process for nanofabrication. We will present partial solutions to a few of them.

Published in:

Nano/Micro Engineered and Molecular Systems (NEMS), 2012 7th IEEE International Conference on

Date of Conference:

5-8 March 2012