By Topic

A method based on the granger causality and graph kernels for discriminating resting state from attentional task

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Danesh Shahnazian ; Control and Intelligent Processing Center of Excellence, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, 14395-515, Iran ; Fatemeh Mokhtari ; Gholam-Ali Hossein-Zadeh

Exploring the directional connections between brain regions is of great importance in understanding the brain function. As a method of this exploration, Granger causality is defined in terms of the amount of improvement in the estimation of a signal by past samples of another signal (cause). This method produced reliable results in various applications. In current study, we use connections of directed graphs as the features for discriminating two brain states, rest and attentional cueing task, in a block design fMRI dataset. We apply a support vector machine (SVM) which is enriched by graph kernels like random walk, graphlet and sub-tree kernels on directed graphs of different brain states. Graph kernel methods are a branch of graph matching methods and have recently been proposed as a theoretically sound and promising approach to the problem of graph comparison. They measure the inexact similarity between graphs. For the first time, we apply graph kernels on graphs of brain's effective connectivity. We achieved classification accuracy of 100% in discrimination of resting state from attentional task. We also obtain one graph for each brain state representing causal connections between brain regions. From the networks obtained for each state, we can infer that caudate is the source of information in both states and Left ventromedial prefrontal is the sink of information in the resting state.

Published in:

Biomedical Engineering (ICoBE), 2012 International Conference on

Date of Conference:

27-28 Feb. 2012