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Previous literature has suggested that psychological state may be changed via drinking coke, however, studies empirically documenting the link between coke and blood pressure wave (BPW) are scant. Therefore, the current article attempts to explore how coke intervene the mental condition with the assessment of pulse signal recordings. The quantitative analysis of the data was conducted through SAS, EXCEL and MATLAB package software in order to find a specific pattern of pulse spectrum. Results of this study showed the high frequency of heart rate variability increased from 34.83 to 43.83, and that of beat-to-beat pulse variability was enhanced from 7.67 to 35.5. The value of beat-to beat pulse variability in time-domain also went up. The relationship between sd1 and sd2 of RRI and HRV are positively correlated.