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The collaborative networks paradigm can empower enterprises with the needed agility and survival capability to face market turbulence. However, the success and sustainability of collaboration requires proper understanding and modeling of the involved behavioral aspects, a basis for sound development of support tools and governance mechanisms. Therefore a set of relevant behavior-related issues are discussed and major research challenges identified. This includes network's evolution, emotional health, incentives, conflicts preemption and negotiation, value systems alignment, collaboration readiness, and governance principles.