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Biology image is a main approach of biology research, So the measurement and recognition accurately of biology image, especially the monometer image like cell image, is very important and critical. All these depend on the accurate display of biology image. A key model of standard display function(SDF) for biology image is established at cell level, and measurement images are calibrated by the metrology standard of image using this model. The biology image can be appeared more “true” through this calibration. The SDF of several serial image data at key wavelengths are calibrated using the model, and then these serial data are combined in one image, thus the calibration is achieved. A kind of human erythrocyte image is measured and calibrated correspondly. After calibrated, the chromatism of this image is improved by 3 and the luminance contrast of that is improved by 2.