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Due to its proven capability in customizing information according to the patients' needs, multimedia has been regarded as a promising technology for home healthcare. In this paper, we present our study on improving medication adherence of the elderly with the support of ubiquitous multimedia services. A multimedia healthcare system (MHS) is built based on a comprehensive understanding of the requirements of the elderly care. It provides the continuous medication monitoring, context aware prompting, adaptive multimedia presentation, and flexible medicine management. The experimental results show that the MHS can improve the medication adherence of the elderly effectively.