By Topic

The preliminary study of antiproliferative effect on MCF-7 cells of Rhodiola algida Var. tangutica

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Dianxiang Lu ; Res. Center for High Altitude Med., Qinghai Univ., Xining, China ; Shu-na Zhang ; Rili Ge ; Dianjun Lu

The anti-tumor effect of Rhodiola algida Var. tangutica in vitro was researched in this article. HPLC analysis of the aqueous extract defined the presence of salidroside and tyrosol. The results of MTT assay showed that the extract reduces survival of MCF-7 tumor cells markedly. Microscopic observation confirmed the apoptosis of the tumor cells after being treated by the extract. Some cells containing vacuoles and apoptotic bodies were observed. The FCM analysis showed that lower concentrations of the extract caused much apoptotic cells and higher concentrations led to much necrotic cells.

Published in:

Complex Medical Engineering (CME), 2011 IEEE/ICME International Conference on

Date of Conference:

22-25 May 2011