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An Electronic Circuit Model for Simulation of Synaptic Communication: The NEUROISFET for Wireless Biotelemetry

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2 Author(s)
Dutta, J.C. ; Dept of ECE, Tezpur Univ., Tezpur, India ; Roy, S.

A simple electronic circuit is proposed to simulate bio-communication between neurons of our nervous system. In this model, the variable conductance of postsynaptic membrane of neuron dependence on the neurotransmitter-receptor binding activity is represented by ion sensitive field effect transistor (ISFET). ISFET is chosen as circuit analog because it has potential for on-chip circuit integration leading to the development of lab-on-chip system used in advanced wireless biotelemetry. This analog is incorporated into the famous Hodgkin-Huxley (H-H) model of neuron to substitute the variable Na+ conductance. Simulation is performed in MATLAB environment both for normal and pathologic states.

Published in:

Devices and Communications (ICDeCom), 2011 International Conference on

Date of Conference:

24-25 Feb. 2011