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As the transfer channel and tie of modern material flow, energy flow and information flow, highway plays an important role in the whole economic development. The dynamic response characteristics of highway roadbed slope under the action of seismic dynamic loading are analyzed in this paper. Furthermore, the dynamic response rules under the cohesion influence of roadbed soil are analyzed in detail. Finally, the amplification coefficient distribution of acceleration, velocity, displacement and relative displacement are comprehensively analyzed under various cohesions. And the final plastic zone is gained.