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Galled trees, directed acyclic graphs that model evolutionary histories with isolated hybridization events, have become very popular due to both their biological significance and the existence of polynomial-time algorithms for their reconstruction. In this paper, we establish to which extent several distance measures for the comparison of evolutionary networks are metrics for galled trees, and hence, when they can be safely used to evaluate galled tree reconstruction methods.
Computational Biology and Bioinformatics, IEEE/ACM Transactions on (Volume:8 , Issue: 2 )
Date of Publication: March-April 2011