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Computational assessment of spatio-temporal heterogeneity of human left ventricular contractions in normal and ischemic heart

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4 Author(s)
Chumarnaya, T. ; Inst. of Immunology & Physiol., Russian Acad. of Sci., Russia ; Solovyova, O. ; Sukhareva, S.V. ; Markhasin, V.S.

Two-dimensional echocardiographic images of left ventricle are analyzed to characterize quantitatively spatio-temporal heterogeneity of regional wall motion in norm and ischemic heart disease. A negative correlation between the regional heterogeneity and the global ejection fraction is revealed. Regional heterogeneity is shown to increase significantly in patients with ischemic heart disease compared to normal subjects. A special contribution of the apex is identified, and a diagnostic index of regional wall motion abnormality is suggested.

Published in:
Computers in Cardiology, 2009

Date of Conference: 13-16 Sept. 2009

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