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Dual-axes confocal microscopy for clinical skin imaging

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8 Author(s)
Piyawattanametha, W. ; Edward L. Ginzton Lab., Stanford Univ., Stanford, CA, USA ; Ra, H. ; Mandella, M.J. ; Gonzalez, E.
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We demonstrate MEMS based near infrared fluorescence dual-axes confocal (DAC) imaging in a 10-mm-diameter microscope for three-dimensional (3-D) imaging of in vivo human skin. The probe is used to reveal mosaicing two-dimensional (2-D) en face sub-surface histology at depths of up to 250 mum. The probe has a maximum field of view (FOV) of 800times450 mum2 and a maximum acquisition rate of 10 frames/second. The transverse and axial resolutions are 5 mum and 7 mum, respectively.

Published in:

Optical MEMS and Nanophotonics, 2009 IEEE/LEOS International Conference on

Date of Conference:

17-20 Aug. 2009