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Telesurgery systems integrate multimodal communication and robotic technologies to enable surgical procedures to be performed from remote locations. They allow human surgeons to intuitively control laparoscopic instruments and to navigate within the human body. In this paper, we present selected topics on multimodal interaction in the context of telesurgery applications. These are results from the collaborative research project SFB 453 on ldquoHigh-Fidelity Telepresence and Teleactionrdquo which is funded by the German Research Foundation in the larger Munich area. The focus in this paper is on multimodal information processing and communication including simulation of surgical targets in the human body. Furthermore, we present an overview of our advanced multimodal telesurgery demonstrators that provide a comprehensive platform for our collaborative telepresence research.