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A power amplifier designed for use as a biological stimulator is described. It is driven by a dc voltage or a pulse generator with an amplitude of 50 volts. The output power of up to 250 volts and 100 ma is precisely controlled. The rise time is less than 5 Â¿sec. A dual-channel version whose outputs may be independently controlled and mixed is also described. The circuit for the +400 volts and Â¿300 volts regulated power supplies is shown.