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This letter presents two kernel-based methods for semisupervised regression. The methods rely on building a graph or hypergraph Laplacian with both the available labeled and unlabeled data, which is further used to deform the training kernel matrix. The deformed kernel is then used for support vector regression (SVR). Given the high computational burden involved, we present two alternative formulations based on the Nystrom method and the incomplete Cholesky factorization to achieve operational processing times. The semisupervised SVR algorithms are successfully tested in multiplatform leaf area index estimation and oceanic chlorophyll concentration prediction. Experiments are carried out with both multispectral and hyperspectral data, demonstrating good generalization capabilities when a low number of labeled samples are available, which is usually the case in biophysical parameter retrieval.