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A three-dimensional reference model for wideband multiple-input multiple-output (MIMO) mobile-to-mobile (M-to-M) channels is reviewed. To validate the reference model, an experimental MIMO M-to-M channel-sounding campaign was conducted for M-to-M vehicular communication with vehicles travelling along expressways in a metropolitan area. The measured data is processed and the channel statistics obtained from the reference model and from the empirical measurements are compared. The close agreement between the analytically and empirically obtained channel statistics confirms the utility of the proposed reference model.