Referenced Items are not available for this document.
We describe the design, characterization, and demonstration of a fully integrated single-photon avalanche diode (SPAD) imager for use in time-resolved fluorescence imaging. The imager consists of a 64-by-64 array of active SPAD pixels and an on-chip time-to-digital converter (TDC) based on a delay-locked loop (DLL) and calibrated interpolators. The imager can perform both standard time-correlated single-photon counting (TCSPC) and an alternative gated-window detection useful for avoiding pulse pile-up when measuring bright signal levels. To illustrate the use of the imager, we present measurements of the decay lifetimes of fluorescent dyes of several types with a timing resolution of 350 ps.
Published in:
Solid-State Circuits, IEEE Journal of
(Volume:43
,
Issue:
11
)
Date of Publication: Nov. 2008
- Page(s):
- 2546 - 2557
- ISSN :
- 0018-9200
- INSPEC Accession Number:
- 10324308
- Digital Object Identifier :
- 10.1109/JSSC.2008.2005818
- Product Type:
- Journals & Magazines
- Date of Current Version :
- 21 November 2008
- Issue Date :
- Nov. 2008
- Sponsored by :
- IEEE Solid-State Circuits Society
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