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Speckled Computing is an emerging technology based on the deployment of thousands of minute semiconductor grains in dense, wireless networks known as Specknets. Specknets collect and process data to achieve some application dependent functionality. In this paper, we present the first tier of our three-level framework for Specknets, inspired by the natural innate immune system. In particular, we focus on information gathering by examining corresponding mechanisms in the immune system, from which we derive an initial model. In addition, we discuss simulation of the model and present preliminary experimental results concerned with the coverage of the network during sample collection.