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Telemedicine is a future trend of medical care due to the increasing cost of treatment and the aging of population around the world. Several telecommunication technologies are proposed for transferring medical data between a point of care and a hospital. However, it does not provide full mobility where a patient still needs to be attached with wired monitoring devices. In this paper, we proposed a wireless three-lead electrocardiogram (ECG) device using a mote-based wireless sensor network (WSN) to transfer heart signals from a patient to a personal computer for monitoring and storing. Our proposed device augments the mote-based Telos node and TinyOS. The experiment results show the similarity of the ECG signals between our three-lead wireless ECG device and a wired commercial ECG device.