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Identify the gene positions of methylated DNA with a database approach

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5 Author(s)
Wenyi Bi ; Computer Science Department, Cheyney University of Pennsylvania, 19319, USA ; John Dunn ; Sean McCorkle ; Reginald Gabriel
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Determining the global pattern of DNA methylation, or the methylome and its variation in cells has become an area of considerable interest primarily because of its potential use as an early diagnostic biomarker for cancers. Genome survey techniques are now being used to identify heavily methylated regions on a massive scale and there is a need to correlate this data with focused biomedical information in a high-throughput manner. Towards this end, we present a database which combines genomic location of methylation sites, genes, CpG islands with specialized genetic-ontological resources which allow for large scale comprehensive presentations of utility to researchers.

Published in:

2007 IEEE International Conference on Systems, Man and Cybernetics

Date of Conference:

7-10 Oct. 2007