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A 10T/pixel CMOS digital pixel sensor with clock count output, ultra low supply voltage, and wide dynamic range is presented. The pixel fabricated by a standard 0.25-μm CMOS logic process comprises a reset transistor, a photo-diode, a comparator, and an inverter with pixel size of 9.4×9.4 μm2 and 24% fill factor. The amplified logarithmic output response similar to the light response of human eye is demonstrated in this work. The pixel can operate at a supply voltage as low as 1.2 V without affecting its output characteristics. The dynamic range of this cell limited by either the subsequent analog-to-digital circuit resolution or the rising and falling time of output clock is higher than 90 dB with an 8-bit resolution.