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Examining coding structure and redundancy in DNA

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1 Author(s)
Rosen, G.L. ; Center for Signal & Image Process., Georgia Inst. of Technol., Atlanta, GA, USA

A review of DNA signal content, redundancy, and mutational mechanisms is presented. Mutation-robust methods are developed to detect a linear coding structure and approximate tandem repeats. In this article, a method to uncover an error-correction coding structure in the nucleotide sequence is developed and its efficiency in detecting approximate tandem repeats, such as microsatellite regions, is demonstrated.

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Engineering in Medicine and Biology Magazine, IEEE  (Volume:25 ,  Issue: 1 )