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Patterns of gene deletion following genome duplication in yeast

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2 Author(s)
J. K. Byrnes ; Dept. of Ecology & Evolution, Chicago Univ., IL, USA ; W. -H. Li

Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following WGD in yeast with simulations. We find that deletion events alternate between paralogous chromosomes more often than expected under a random duplicate deletion model.

Published in:

2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05)

Date of Conference:

8-11 Aug. 2005