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A cascade mode magnetophoretic microseparator for high efficiency blood cell separations

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2 Author(s)
Ki-Ho Han ; Sch. of Electr. & Comput. Eng., Georgia Inst. of Technol., Atlanta, GA, USA ; Bruno Frazier, A.

This paper presents the design, fabrication, and characterization of a high efficiency blood cell separator based on a cascade design of the continuous paramagnetic capture mode magnetophoretic microseparator. The PMC cascade microseparator directly separates blood cells from whole blood based on their native magnetic properties using a high gradient magnetic field without the use of additives such as magnetic tagging or fluorescent dyes. Experimental results show that 93.5 % of red blood cells and 97.4 % of white blood cells, from whole blood, was separated within 5 minutes by using a conventional permanent magnet to create an external magnetic flux of 0.2 T.

Published in:

Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on  (Volume:2 )

Date of Conference:

5-9 June 2005