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An in-plane microneedles used for sampling and glucose analysis

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5 Author(s)
Liu, R. ; Dept. of Precision Instruments & Mechanology, Tsinghua Univ., Beijing, China ; Wang, X.H. ; Tang, F. ; Feng, Y.Y.
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We report here the design, fabrication and experiments of a hollow in-plane microneedle, with which a biosensor is integrated to extract interstitial fluid from skin for glucose measurement. The design of hollow in-plane microneedles leads to a simple fabrication process. Different from common methods for immobilizing enzyme, we use capillary force to immobilize enzyme on the surface of microelectrodes. The experimental results showed a good linearity for the characteristic curve of glucose concentration, when it varies from 0 to 500mg/dl with respect to current signal value. The sensitivity of 0.4238nA was obtained.

Published in:

Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on  (Volume:2 )

Date of Conference:

5-9 June 2005