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It is argued that iterative signal cancellation receivers, with or without the use of error control coding, are preferred for practically viable multiuser detection. Achievable spectral efficiencies are calculated for both cases and arguments are given on how to achieve maximum spectral efficiencies by rate or power layering of the different users in a multiple access environment. The achievable spectral efficiencies of iterative cancellation receivers, which include error control codes, are compared to those which do not. The latter are found to be essentially viable only in power controlled environments.